thalidomide has been researched along with Musculoskeletal Diseases in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Musculoskeletal Diseases: Diseases of the muscles and their associated ligaments and other connective tissue and of the bones and cartilage viewed collectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The drug caused severe birth defects." | 2.58 | The changing health of Thalidomide survivors as they age: A scoping review. ( Atkin, K; Newbronner, E, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Newbronner, E | 1 |
| Atkin, K | 1 |
| O'Carroll, A | 1 |
| O'Reilly, F | 1 |
| Whitford, DL | 1 |
1 review available for thalidomide and Musculoskeletal Diseases
| Article | Year |
|---|---|
The changing health of Thalidomide survivors as they age: A scoping review.
Topics: Aging; Comorbidity; Congenital Abnormalities; Disabled Persons; Female; Health Status; Humans; Menta | 2018 |
1 other study available for thalidomide and Musculoskeletal Diseases
| Article | Year |
|---|---|
What has happened to people affected by thalidomide 50 years on?
Topics: Activities of Daily Living; Adult; Arm; Disabled Persons; Female; Health Status; Humans; Leg; Male; | 2011 |