thalidomide has been researched along with Muscle Spasticity in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simon, AJ | 1 |
| Lev, A | 1 |
| Zhang, Y | 1 |
| Weiss, B | 1 |
| Rylova, A | 1 |
| Eyal, E | 1 |
| Kol, N | 1 |
| Barel, O | 1 |
| Cesarkas, K | 1 |
| Soudack, M | 1 |
| Greenberg-Kushnir, N | 1 |
| Rhodes, M | 1 |
| Wiest, DL | 1 |
| Schiby, G | 1 |
| Barshack, I | 1 |
| Katz, S | 1 |
| Pras, E | 1 |
| Poran, H | 1 |
| Reznik-Wolf, H | 1 |
| Ribakovsky, E | 1 |
| Simon, C | 1 |
| Hazou, W | 1 |
| Sidi, Y | 1 |
| Lahad, A | 1 |
| Katzir, H | 1 |
| Sagie, S | 1 |
| Aqeilan, HA | 1 |
| Glousker, G | 1 |
| Amariglio, N | 1 |
| Tzfati, Y | 1 |
| Selig, S | 1 |
| Rechavi, G | 1 |
| Somech, R | 1 |
1 other study available for thalidomide and Muscle Spasticity
| Article | Year |
|---|---|
Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.
Topics: Animals; Ataxia; Brain Neoplasms; Calcinosis; Central Nervous System Cysts; Disease Models, Animal; | 2016 |