thalidomide has been researched along with Muscle Disorders in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case shows that AL amyloidosis from light-chain deposition disease may predominantly affect the intestines, myocardium and the skeletal muscle and that lenalidomide may have a beneficial effect on the amyloidosis but should be given with caution for its potential arrhythmogenic and thrombogenic side-effects." | 7.79 | Sudden death possibly related to lenalidomide given for cardiac and muscle AL amyloidosis secondary to light chain deposition disease. ( Finsterer, J; Höftberger, R; Regele, H; Stöllberger, C; Wöhrer, A, 2013) |
| "Thalidomide was effective for muscular, cutaneous, and pulmonary involvement in our patient." | 5.32 | Successful treatment of muscle sarcoidosis with thalidomide. ( Lochmüller, H; Meindl, T; Müller-Felber, W; Schlotter-Weigel, B; Walter, MC, 2003) |
| "This case shows that AL amyloidosis from light-chain deposition disease may predominantly affect the intestines, myocardium and the skeletal muscle and that lenalidomide may have a beneficial effect on the amyloidosis but should be given with caution for its potential arrhythmogenic and thrombogenic side-effects." | 3.79 | Sudden death possibly related to lenalidomide given for cardiac and muscle AL amyloidosis secondary to light chain deposition disease. ( Finsterer, J; Höftberger, R; Regele, H; Stöllberger, C; Wöhrer, A, 2013) |
| "Thalidomide was effective for muscular, cutaneous, and pulmonary involvement in our patient." | 1.32 | Successful treatment of muscle sarcoidosis with thalidomide. ( Lochmüller, H; Meindl, T; Müller-Felber, W; Schlotter-Weigel, B; Walter, MC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gremain, V | 1 |
| Litrowski, N | 1 |
| Boulard, C | 1 |
| Marguet, F | 1 |
| Courville, P | 1 |
| Zarnitsky, C | 1 |
| Langlois, V | 1 |
| Finsterer, J | 1 |
| Höftberger, R | 1 |
| Stöllberger, C | 1 |
| Wöhrer, A | 1 |
| Regele, H | 1 |
| Walter, MC | 1 |
| Lochmüller, H | 1 |
| Schlotter-Weigel, B | 1 |
| Meindl, T | 1 |
| Müller-Felber, W | 1 |
| Wu, MY | 1 |
| Hong, JB | 1 |
| Yang, CC | 1 |
| Hu, SL | 1 |
| Liao, YH | 1 |
| Johansson, B | 1 |
1 review available for thalidomide and Muscle Disorders
| Article | Year |
|---|---|
[Side effects of drugs. 4. Drug induced polyneuropathies and myopathies].
Topics: Adrenocorticotropic Hormone; Chloroquine; Glucocorticoids; Humans; Hydralazine; Isoniazid; Muscular | 1969 |
4 other studies available for thalidomide and Muscle Disorders
| Article | Year |
|---|---|
Necrotizing autoimmune myopathy associated with POEMS syndrome report.
Topics: Autoimmune Diseases; Dexamethasone; Electromyography; Humans; Lenalidomide; Male; Middle Aged; Muscu | 2018 |
Sudden death possibly related to lenalidomide given for cardiac and muscle AL amyloidosis secondary to light chain deposition disease.
Topics: Aged; Amyloidosis; Biopsy; Cardiomyopathy, Restrictive; Fatal Outcome; Female; Humans; Immunoglobuli | 2013 |
Successful treatment of muscle sarcoidosis with thalidomide.
Topics: Adult; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Muscular Diseases; Sarcoi | 2003 |
Scleromyxedema with myopathy was successfully treated by thalidomide.
Topics: Biopsy; Female; Humans; Middle Aged; Muscular Diseases; Scleromyxedema; Thalidomide | 2009 |