thalidomide has been researched along with Muscle Contraction in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We recently reported, that thalidomide reduces prostate smooth muscle contraction and inhibits cell growth." | 8.02 | Lenalidomide and pomalidomide inhibit growth of prostate stromal cells and human prostate smooth muscle contraction. ( Ciotkowska, A; Gratzke, C; Hennenberg, M; Huang, R; Li, B; Rutz, B; Sauckel, C; Stief, CG; Tamalunas, A; Wang, R, 2021) |
| " We recently reported, that thalidomide reduces prostate smooth muscle contraction and inhibits cell growth." | 4.02 | Lenalidomide and pomalidomide inhibit growth of prostate stromal cells and human prostate smooth muscle contraction. ( Ciotkowska, A; Gratzke, C; Hennenberg, M; Huang, R; Li, B; Rutz, B; Sauckel, C; Stief, CG; Tamalunas, A; Wang, R, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamalunas, A | 2 |
| Sauckel, C | 2 |
| Ciotkowska, A | 2 |
| Rutz, B | 2 |
| Wang, R | 2 |
| Huang, R | 2 |
| Li, B | 2 |
| Stief, CG | 2 |
| Gratzke, C | 2 |
| Hennenberg, M | 2 |
| Ismail, B | 1 |
| Aboul-Fotouh, S | 1 |
| Mansour, AA | 1 |
| Shehata, HH | 1 |
| Salman, MI | 1 |
| Ibrahim, EA | 1 |
| Hassan, OA | 1 |
| Abdel-tawab, AM | 1 |
| Fernández-Martínez, E | 1 |
| Ponce-Monter, H | 1 |
| Soria-Jasso, LE | 1 |
| Ortiz, MI | 1 |
| Arias-Montaño, JA | 1 |
| Barragán-Ramírez, G | 1 |
| Mayén-García, C | 1 |
| Matthiab, HH | 1 |
| Ruffing, L | 1 |
| Weinert, C | 1 |
5 other studies available for thalidomide and Muscle Contraction
| Article | Year |
|---|---|
Inhibition of human prostate stromal cell growth and smooth muscle contraction by thalidomide: A novel remedy in LUTS?
Topics: Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Humans; Lower Urinary Tract Symptoms; Male; | 2021 |
Lenalidomide and pomalidomide inhibit growth of prostate stromal cells and human prostate smooth muscle contraction.
Topics: Apoptosis; Cell Line, Transformed; Humans; Lenalidomide; Male; Muscle Contraction; Muscle, Smooth; P | 2021 |
Behavioural, metabolic, and endothelial effects of the TNF-α suppressor thalidomide on rats subjected to chronic mild stress and fed an atherogenic diet.
Topics: Animals; Antidepressive Agents, Tricyclic; Aorta, Thoracic; Atherosclerosis; Chronic Disease; Depres | 2014 |
Inhibition of Uterine Contractility by Thalidomide Analogs via Phosphodiesterase-4 Inhibition and Calcium Entry Blockade.
Topics: Adolescent; Adult; Calcium; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP; Dose-Response Rel | 2016 |
[An examination programme for functional analysis of the upper extremities (author's transl)].
Topics: Abnormalities, Drug-Induced; Adult; Arm; Ectromelia; Female; Fingers; Humans; Male; Motor Skills; Mu | 1981 |