thalidomide has been researched along with Morphine Dependence in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine dependence and the subsequent withdrawal syndrome restrict its clinical use in management of chronic pain." | 7.88 | Thalidomide attenuates development of morphine dependence in mice by inhibiting PI3K/Akt and nitric oxide signaling pathways. ( Dehpour, AR; Ejtemaei-Mehr, S; Jahanabadi, S; Khan, MI; Momeny, M; Ostadhadi, S; Sameem, B; Zarrinrad, G, 2018) |
| "Morphine dependence and the subsequent withdrawal syndrome restrict its clinical use in management of chronic pain." | 3.88 | Thalidomide attenuates development of morphine dependence in mice by inhibiting PI3K/Akt and nitric oxide signaling pathways. ( Dehpour, AR; Ejtemaei-Mehr, S; Jahanabadi, S; Khan, MI; Momeny, M; Ostadhadi, S; Sameem, B; Zarrinrad, G, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, MI | 1 |
| Momeny, M | 1 |
| Ostadhadi, S | 1 |
| Jahanabadi, S | 1 |
| Ejtemaei-Mehr, S | 1 |
| Sameem, B | 1 |
| Zarrinrad, G | 1 |
| Dehpour, AR | 1 |
| DE JONGE, GA | 1 |
| Modell, W | 1 |
| Miller, CO | 1 |
4 other studies available for thalidomide and Morphine Dependence
| Article | Year |
|---|---|
Thalidomide attenuates development of morphine dependence in mice by inhibiting PI3K/Akt and nitric oxide signaling pathways.
Topics: Animals; Cell Line, Tumor; Central Nervous System Agents; Hippocampus; Humans; Male; Mice; Morphine; | 2018 |
[FETAL DAMAGE CAUSED BY PHARMACEUTICAL AGENTS].
Topics: Abnormalities, Drug-Induced; Endocrine System Diseases; Fetal Diseases; Humans; Morphine Dependence; | 1965 |
Mass drug catastrophes and the roles of science and technology.
Topics: Alcoholism; Caffeine; Cannabis; Central Nervous System; Cocaine; Drug Hypersensitivity; Hallucinogen | 1967 |
Toxicology: use of nonhuman primates.
Topics: Abnormalities, Drug-Induced; Animals; Central Nervous System; Drug-Related Side Effects and Adverse | 1967 |