thalidomide has been researched along with Meningeal Neoplasms in 8 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Meningeal Neoplasms: Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Multiple myeloma is an incurable clonal B-cell malignancy with terminally differentiated plasma cells that accounts for 1% of all malignancies in the United States." | 2.46 | Intracranial multifocal dural involvement in multiple myeloma: case report and review of the literature. ( Destian, S; Hwang, BJ; Jagannath, S; Mazumder, A; Méndez, CE; Vesole, DH, 2010) |
| "Thalidomide has been reported to have anti-AML activity and appears to cross the blood brain barrier (BBB)." | 1.32 | Thalidomide is highly effective in a patient with meningeal acute myeloid leukaemia. ( Baird, R; Duddy, J; Iveson, A; Rassam, SM; van Zyl-Smit, RN, 2004) |
| "She was diagnosed as having multiple myeloma and transferred to our department." | 1.32 | [Multiple myeloma of the IgD-lambda type invading CNS]. ( Aikawa, S; Hatta, Y; Horie, T; Ito, T; Kanbe, E; Kitamura, K; Kura, Y; Oka, H; Saiki, M; Sawada, U; Takeuchi, J; Yamazaki, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bohn, JP | 1 |
| Willenbacher, W | 1 |
| Peschel, I | 1 |
| Oberacher, H | 1 |
| Steurer, M | 1 |
| Ise, M | 1 |
| Sakai, C | 1 |
| Kumagai, K | 1 |
| Fernández Salazar, LI | 1 |
| Velayos Jiménez, B | 1 |
| Fernández Galante, I | 1 |
| Aller de la Fuente, R | 1 |
| González Hernández, JM | 1 |
| Méndez, CE | 1 |
| Hwang, BJ | 1 |
| Destian, S | 1 |
| Mazumder, A | 1 |
| Jagannath, S | 1 |
| Vesole, DH | 1 |
| Vicari, P | 1 |
| Ribas, C | 1 |
| Sampaio, M | 1 |
| Arantes, AM | 1 |
| Yamamoto, M | 1 |
| Filho, JB | 1 |
| Segreto, RA | 1 |
| Bordin, JO | 1 |
| Colleoni, GW | 1 |
| Baird, R | 1 |
| van Zyl-Smit, RN | 1 |
| Iveson, A | 1 |
| Duddy, J | 1 |
| Rassam, SM | 1 |
| Kitamura, K | 1 |
| Takeuchi, J | 1 |
| Kanbe, E | 1 |
| Oka, H | 1 |
| Saiki, M | 1 |
| Aikawa, S | 1 |
| Kura, Y | 1 |
| Hatta, Y | 1 |
| Yamazaki, T | 1 |
| Ito, T | 1 |
| Sawada, U | 1 |
| Horie, T | 1 |
| Yutaka, H | 1 |
| Mariko, Y | 1 |
| Shinichiro, O | 1 |
| Kunihiko, M | 1 |
| Yusuke, T | 1 |
| Yasuo, I | 1 |
1 review available for thalidomide and Meningeal Neoplasms
| Article | Year |
|---|---|
Intracranial multifocal dural involvement in multiple myeloma: case report and review of the literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cisplatin; Cyclophosphami | 2010 |
7 other studies available for thalidomide and Meningeal Neoplasms
| Article | Year |
|---|---|
Second-generation immunomodulatory drugs in leptomeningeal myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Immunologic Facto | 2019 |
Meningeal myelomatosis developed after treatment with novel agents.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Cerebrospinal Fluid | 2013 |
[Efficacy of thalidomide in digestive bleeding caused by angiodysplasias].
Topics: Aged; Angiodysplasia; Angiogenesis Inhibitors; Cardiovascular Diseases; Cerebellar Neoplasms; Cerebe | 2009 |
Can thalidomide be effective to treat plasma cell leptomeningeal infiltration?
Topics: Female; Humans; Meningeal Neoplasms; Middle Aged; Multiple Myeloma; Neoplasm Invasiveness; Plasma Ce | 2003 |
Thalidomide is highly effective in a patient with meningeal acute myeloid leukaemia.
Topics: Adult; Fatal Outcome; Female; Humans; Leukemia, Erythroblastic, Acute; Lymphoma, B-Cell; Meningeal N | 2004 |
[Multiple myeloma of the IgD-lambda type invading CNS].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Dexamethasone; Doxorubicin; Drug Therapy | 2004 |
Thalidomide for the treatment of leptomeningeal multiple myeloma.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Etoposide; Fat | 2006 |