thalidomide has been researched along with Megacolon in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Megacolon: Dilatation of the COLON, often to alarming dimensions. There are various types of megacolon including congenital megacolon in HIRSCHSPRUNG DISEASE, idiopathic megacolon in CONSTIPATION, and TOXIC MEGACOLON.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MATTURRI, L | 1 |
| NODARI, R | 1 |
| PARTSCH, CJ | 1 |
| Wuest, HM | 1 |
| Fox, RR | 1 |
| Crary, DD | 1 |
3 other studies available for thalidomide and Megacolon
| Article | Year |
|---|---|
[ANATOMOCLINICAL STUDY OF 19 CASES OF EMBRYOPATHY CAUSED BY THALIDOMIDE].
Topics: Appendix; Congenital Abnormalities; Ectromelia; Female; Fetal Diseases; Heart Defects, Congenital; H | 1963 |
[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Congenital Abnormalities; Cryptorchidism; Ear Deformities | 1964 |
Relationship between teratogeny and structure in the thalidomide field.
Topics: Abnormalities, Drug-Induced; Amides; Animals; Aortic Valve Stenosis; Chemical Phenomena; Chemistry; | 1968 |