thalidomide has been researched along with Mediastinal Neoplasms in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Mediastinal Neoplasms: Tumors or cancer of the MEDIASTINUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The case history of a fifteen year old patient with Thalidomide induced malformation who developed a lymphoma of high malignancy is presented." | 7.66 | [Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)]. ( Horwitz, A; Kosenow, W; Miller, A; Schmidt, CG, 1980) |
| "The case history of a fifteen year old patient with Thalidomide induced malformation who developed a lymphoma of high malignancy is presented." | 3.66 | [Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)]. ( Horwitz, A; Kosenow, W; Miller, A; Schmidt, CG, 1980) |
| "Mediastinal nonseminomatous germ cell tumor (MNSGCT)-associated histiocytic proliferations are rare and rapidly fatal disorders." | 1.43 | Mediastinal Germ Cell Tumor-associated Histiocytic Proliferations Treated With Thalidomide Plus Chemotherapy Followed by Alemtuzumab-containing Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation: A Case Report. ( Chen, RL; Chen, WT; Fang, LH; Lee, PI; Shih, LS, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quilodrán, JA | 1 |
| Peña, C | 1 |
| Valladares, X | 1 |
| Sharman, JP | 1 |
| Chmielecki, J | 1 |
| Morosini, D | 1 |
| Palmer, GA | 1 |
| Ross, JS | 1 |
| Stephens, PJ | 1 |
| Stafl, J | 1 |
| Miller, VA | 1 |
| Ali, SM | 1 |
| Salem, KZ | 1 |
| Nishihori, T | 1 |
| Kharfan-Dabaja, MA | 1 |
| Horna, P | 1 |
| Alsina, M | 1 |
| Fang, LH | 1 |
| Shih, LS | 1 |
| Lee, PI | 1 |
| Chen, WT | 1 |
| Chen, RL | 1 |
| Rick, O | 1 |
| Braun, T | 1 |
| Siegert, W | 1 |
| Beyer, J | 1 |
| Miller, A | 1 |
| Schmidt, CG | 1 |
| Horwitz, A | 1 |
| Kosenow, W | 1 |
6 other studies available for thalidomide and Mediastinal Neoplasms
| Article | Year |
|---|---|
[Extramedullary mediastinal plasmacytoma. Report of one case].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Humans; Male; Mediastinal Neoplasms; Mediastin | 2017 |
Vemurafenib response in 2 patients with posttransplant refractory BRAF V600E-mutated multiple myeloma.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezom | 2014 |
Primary plasmacytoma involving mediastinal lymph nodes: A diagnostic mimicry of primary mediastinal lymphoma.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Humans; Lenalidomide; Lymph Nodes; Male; | 2016 |
Mediastinal Germ Cell Tumor-associated Histiocytic Proliferations Treated With Thalidomide Plus Chemotherapy Followed by Alemtuzumab-containing Reduced Intensity Allogeneic Peripheral Blood Stem Cell Transplantation: A Case Report.
Topics: Alemtuzumab; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Fatal Outcome; Histiocytic Sa | 2016 |
Activity of thalidomide in patients with platinum-refractory germ-cell tumours.
Topics: Adult; Antineoplastic Agents; Drug Resistance, Neoplasm; Gonadal Disorders; Humans; Mediastinal Neop | 2006 |
[Coincidence of a thalidomide-induced malformation and a lymphoma of high malignancy (author's transl)].
Topics: Abnormalities, Drug-Induced; Adolescent; Female; Humans; Lymphoma; Mediastinal Neoplasms; Pathology; | 1980 |