Page last updated: 2024-11-05

thalidomide and Malocclusion

thalidomide has been researched along with Malocclusion in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Malocclusion: Such malposition and contact of the maxillary and mandibular teeth as to interfere with the highest efficiency during the excursive movements of the jaw that are essential for mastication. (Jablonski, Illustrated Dictionary of Dentistry, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ekfeldt, A1
Carlsson, GE1
Stahl, A2

Other Studies

3 other studies available for thalidomide and Malocclusion

ArticleYear
Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study.
    Acta odontologica Scandinavica, 2008, Volume: 66, Issue:5

    Topics: Abnormalities, Drug-Induced; Anodontia; Dental Care for Disabled; Dental Caries; DMF Index; Female;

2008
[Dysgnathias in the deciduous dentition in dysmelia: contribution to thalidomide embryopathy].
    Fortschritte der Kieferorthopadie, 1966, Volume: 27, Issue:4

    Topics: Abnormalities, Drug-Induced; Child; Child, Preschool; Dentition; Diastema; Ectromelia; Female; Human

1966
Clinical, orthodontic and radiological findings in the jaws and face of children with dysmelia associated with thalidomide-embryopathy.
    International dental journal, 1968, Volume: 18, Issue:3

    Topics: Abnormalities, Drug-Induced; Ankylosis; Cephalometry; Child, Preschool; Cleft Lip; Cleft Palate; Fem

1968