Page last updated: 2024-11-05

thalidomide and Lymphoma, AIDS-Related

thalidomide has been researched along with Lymphoma, AIDS-Related in 7 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Lymphoma, AIDS-Related: B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.

Research Excerpts

ExcerptRelevanceReference
"A patient with AIDS was diagnosed with inflammatory pseudotumor with small bowel involvement."5.31Inflammatory pseudotumor causing small bowel obstruction and mimicking lymphoma in a patient with AIDS: clinical improvement after initiation of thalidomide treatment. ( Aboulafia, DM, 2000)
"A patient with AIDS was diagnosed with inflammatory pseudotumor with small bowel involvement."1.31Inflammatory pseudotumor causing small bowel obstruction and mimicking lymphoma in a patient with AIDS: clinical improvement after initiation of thalidomide treatment. ( Aboulafia, DM, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Lurain, K1
Ramaswami, R1
Mangusan, R1
Widell, A1
Ekwede, I1
George, J1
Ambinder, R1
Cheever, M1
Gulley, JL1
Goncalves, PH1
Wang, HW1
Uldrick, TS1
Yarchoan, R1
Gupta, NK1
Wang, CC1
Mannis, GN1
Yu, JJ1
Rubenstein, JL1
Yanamandra, U1
Sahu, KK1
Jain, N1
Prakash, G1
Saikia, U1
Malhotra, P1
Stewart, JM1
Krishnamurthy, S1
Jung, CP1
Emmerich, B1
Goebel, FD1
Bogner, JR1
Larson, ML1
Enschede, SH1
Gregory, SA1
Aboulafia, DM1

Reviews

1 review available for thalidomide and Lymphoma, AIDS-Related

ArticleYear
HIV-related lymphoma treated with maintenance thalidomide.
    Clinical advances in hematology & oncology : H&O, 2005, Volume: 3, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antine

2005

Other Studies

6 other studies available for thalidomide and Lymphoma, AIDS-Related

ArticleYear
Use of pembrolizumab with or without pomalidomide in HIV-associated non-Hodgkin's lymphoma.
    Journal for immunotherapy of cancer, 2021, Volume: 9, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Che

2021
Regression of methotrexate-resistant AIDS-related primary central nervous system lymphoma with lenalidomide plus combination anti-retroviral therapy.
    Leukemia & lymphoma, 2017, Volume: 58, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretro

2017
Plasmablastic lymphoma: successful management with CHOP and lenalidomide in resource constraint settings.
    Annals of hematology, 2016, Volume: 95, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans

2016
Fine-needle aspiration cytology of a case of HIV-associated anaplastic myeloma.
    Diagnostic cytopathology, 2002, Volume: 27, Issue:4

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adult; Anti-HIV Agents; Antigens, CD; Biomarkers, Tumor;

2002
Successful treatment of a patient with HIV-associated multicentric Castleman disease (MCD) with thalidomide.
    American journal of hematology, 2004, Volume: 75, Issue:3

    Topics: Adult; Angiogenesis Inhibitors; Castleman Disease; HIV Infections; Humans; Immunosuppressive Agents;

2004
Inflammatory pseudotumor causing small bowel obstruction and mimicking lymphoma in a patient with AIDS: clinical improvement after initiation of thalidomide treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 30, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-HIV Agents; Diagnosis, Differential; Granuloma, Plas

2000