thalidomide has been researched along with Lymph Node Metastasis in 14 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has been reported to have antitumor activity for treating metastatic hepatocellular carcinoma (HCC)." | 7.73 | Thalidomide for treating metastatic hepatocellular carcinoma: a pilot study. ( Bang, SM; Cho, EK; Han, SH; Kim, JH; Kim, KK; Kim, SS; Kwon, OS; Kwon, SY; Lee, JH; Lee, JJ; Lee, JN; Nam, E; Park, SH; Park, YH; Shin, DB, 2006) |
| "Curative treatment of aggressive Kaposi sarcoma (KS) with conventional chemotherapy in human immunodeficiency virus (HIV)-infected patients remains difficult." | 5.39 | Clinical activity of lenalidomide in visceral human immunodeficiency virus-related Kaposi sarcoma. ( Burg, S; Crickx, B; Di Lucca, J; Feldman, J; Joly, V; Lariven, S; Marinho, E; Maubec, E; Peytavin, G; Raymond, E; Sarda-Mantel, L; Steff, M, 2013) |
| "Thalidomide has been reported to have antitumor activity for treating metastatic hepatocellular carcinoma (HCC)." | 3.73 | Thalidomide for treating metastatic hepatocellular carcinoma: a pilot study. ( Bang, SM; Cho, EK; Han, SH; Kim, JH; Kim, KK; Kim, SS; Kwon, OS; Kwon, SY; Lee, JH; Lee, JJ; Lee, JN; Nam, E; Park, SH; Park, YH; Shin, DB, 2006) |
| "Fibrolamellar variant of hepatocellular carcinoma (FLHCC) does not have a favorable prognosis than conventional HCC, and there is no difference regarding the response to chemotherapy and the degree of surgical resectability." | 1.40 | Successful multimodal treatment for aggressive metastatic and recurrent fibrolamellar hepatocellular carcinoma in a child. ( Akdemir, ÜÖ; Akyol, G; Boyunağa, Ö; Dalgiç, A; Demiroğullari, B; Eser, EP; Karadeniz, C; Oğuz, A; Okur, A; Pinarli, FG; Yilmaz, G, 2014) |
| "Curative treatment of aggressive Kaposi sarcoma (KS) with conventional chemotherapy in human immunodeficiency virus (HIV)-infected patients remains difficult." | 1.39 | Clinical activity of lenalidomide in visceral human immunodeficiency virus-related Kaposi sarcoma. ( Burg, S; Crickx, B; Di Lucca, J; Feldman, J; Joly, V; Lariven, S; Marinho, E; Maubec, E; Peytavin, G; Raymond, E; Sarda-Mantel, L; Steff, M, 2013) |
| "Treatment of castration-resistant prostate cancer (CRPC) remains a challenge considering that most patients are elderly men with significant comorbidities." | 1.38 | Long-term disease stabilization in a patient with castration-resistant metastatic prostate cancer by the addition of lenalidomide to low-dose dexamethasone and celecoxib. ( Marschner, N; Zaiss, M, 2012) |
| "Hepatic metastasis from colorectal cancer (mCRC) is best treated with a multidisciplinary approach." | 1.35 | Preoperative chemotherapy does not increase morbidity or mortality of hepatic resection for colorectal cancer metastases. ( Campbell, ML; Landry, CS; Martin, RC; McMasters, KM; Scoggins, CR; Slomiany, BA; Woodall, CE, 2009) |
| "We present a patient with renal carcinoma of the left kidney who underwent laparoscopic extrafascial nephrectomy and adrenalectomy." | 1.33 | Major response and clinical benefit following third-line treatment for Bellini duct carcinoma. ( Balassy, C; Fakhrai, N; Haitel, A; Schmidinger, M; Zielinski, CC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, Z | 1 |
| Zhou, R | 1 |
| Liu, C | 1 |
| Wang, Y | 1 |
| Zhan, W | 1 |
| Shao, Z | 1 |
| Liu, J | 1 |
| Zhang, F | 1 |
| Xu, L | 1 |
| Zhou, X | 1 |
| Qi, L | 1 |
| Bo, F | 1 |
| Ding, Y | 1 |
| Zhao, L | 1 |
| Steff, M | 1 |
| Joly, V | 1 |
| Di Lucca, J | 1 |
| Feldman, J | 1 |
| Burg, S | 1 |
| Sarda-Mantel, L | 1 |
| Peytavin, G | 1 |
| Marinho, E | 1 |
| Crickx, B | 1 |
| Raymond, E | 1 |
| Lariven, S | 1 |
| Maubec, E | 1 |
| Okur, A | 1 |
| Eser, EP | 1 |
| Yilmaz, G | 1 |
| Dalgiç, A | 1 |
| Akdemir, ÜÖ | 1 |
| Oğuz, A | 1 |
| Karadeniz, C | 1 |
| Akyol, G | 1 |
| Demiroğullari, B | 1 |
| Boyunağa, Ö | 1 |
| Pinarli, FG | 1 |
| Harshman, LC | 1 |
| Li, M | 1 |
| Srinivas, S | 2 |
| Scoggins, CR | 1 |
| Campbell, ML | 1 |
| Landry, CS | 1 |
| Slomiany, BA | 1 |
| Woodall, CE | 1 |
| McMasters, KM | 1 |
| Martin, RC | 1 |
| Chen, JR | 1 |
| Tzen, CY | 1 |
| Yang, YC | 1 |
| Marschner, N | 1 |
| Zaiss, M | 1 |
| Haidar, JH | 1 |
| Bazarbachi, A | 1 |
| Nasr, MR | 1 |
| El-Sabban, ME | 1 |
| Daher, R | 1 |
| Fakhrai, N | 1 |
| Haitel, A | 1 |
| Balassy, C | 1 |
| Zielinski, CC | 1 |
| Schmidinger, M | 1 |
| Guardino, AE | 1 |
| Vaishampayan, UN | 1 |
| Heilbrun, LK | 1 |
| Shields, AF | 1 |
| Lawhorn-Crews, J | 1 |
| Baranowski, K | 1 |
| Smith, D | 1 |
| Flaherty, LE | 1 |
| Han, SH | 1 |
| Park, SH | 1 |
| Kim, JH | 2 |
| Lee, JJ | 1 |
| Kwon, SY | 1 |
| Kwon, OS | 1 |
| Kim, SS | 1 |
| Kim, KK | 1 |
| Park, YH | 1 |
| Lee, JN | 1 |
| Nam, E | 1 |
| Bang, SM | 1 |
| Cho, EK | 1 |
| Shin, DB | 1 |
| Lee, JH | 1 |
| Kanwar, VS | 1 |
| Heath, J | 1 |
| Krasner, CN | 1 |
| Pearce, JM | 1 |
| Pollard, M | 1 |
3 trials available for thalidomide and Lymph Node Metastasis
| Article | Year |
|---|---|
The combination of thalidomide and capecitabine in metastatic renal cell carcinoma -- is not the answer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Capecitabine; Carcinoma, Renal | 2008 |
A lower dose of thalidomide is better than a high dose in metastatic renal cell carcinoma.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Bone Neoplasms; Carcinoma, Renal Cell; Double-Blin | 2005 |
Phase II trial of interferon and thalidomide in metastatic renal cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Carcino | 2007 |
11 other studies available for thalidomide and Lymph Node Metastasis
| Article | Year |
|---|---|
MicroRNA-105 is involved in TNF-α-related tumor microenvironment enhanced colorectal cancer progression.
Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Dis | 2017 |
Clinical activity of lenalidomide in visceral human immunodeficiency virus-related Kaposi sarcoma.
Topics: AIDS-Related Opportunistic Infections; Angiogenesis Inhibitors; Antiretroviral Therapy, Highly Activ | 2013 |
Successful multimodal treatment for aggressive metastatic and recurrent fibrolamellar hepatocellular carcinoma in a child.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Child; Cisplatin; Combine | 2014 |
Preoperative chemotherapy does not increase morbidity or mortality of hepatic resection for colorectal cancer metastases.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherap | 2009 |
Metronomic paclitaxel and thalidomide for rapidly metastatic primary vulvar malignant rhabdoid tumor.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Sched | 2009 |
Long-term disease stabilization in a patient with castration-resistant metastatic prostate cancer by the addition of lenalidomide to low-dose dexamethasone and celecoxib.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Castration; Celecoxib; Dexamethasone | 2012 |
Signet ring-like light chain myeloma with systemic spread.
Topics: Anemia; Antineoplastic Agents; Bone Marrow Examination; Combined Modality Therapy; Diagnostic Errors | 2003 |
Major response and clinical benefit following third-line treatment for Bellini duct carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cispla | 2005 |
Thalidomide for treating metastatic hepatocellular carcinoma: a pilot study.
Topics: Adult; Bone Neoplasms; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Humans; Immunosuppressi | 2006 |
Advanced small cell carcinoma of the ovary in a seventeen-year-old female, successfully treated with surgery and multi-agent chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bleomycin; Carcinoma, Small | 2008 |
Thalidomide promotes metastasis of prostate adenocarcinoma cells (PA-III) in L-W rats.
Topics: Adenocarcinoma; Animals; Immunosuppressive Agents; Lung Neoplasms; Lymphatic Metastasis; Male; Neopl | 1996 |