thalidomide has been researched along with Lupus Erythematosus Panniculitis in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lenalidomide was effective for the treatment of CLE (particularly DLE) but not for the treatment of lupus panniculitis in this series." | 1.43 | Lenalidomide treatment of cutaneous lupus erythematosus: the Mayo Clinic experience. ( Davis, MD; Kindle, SA; Pittelkow, MR; Sciallis, GF; Wetter, DA, 2016) |
| "Lupus erythematosus profundus or lupus panniculitis is a rare clinical variant of lupus erythematosus, which involves the deep dermis and subcutaneous fat." | 1.35 | Facets of lupus erythematosus: panniculitis responding to thalidomide. ( Gadola, S; Hunziker, T; Wienert, S, 2008) |
| "A female patient with disfiguring lupus erythematosus profundus (LEP) from the age of 13 years was found to have an isolated partial C4 deficiency, with reduced levels of both allotypes, C4A and C4B." | 1.28 | Lupus erythematosus profundus with partial C4 deficiency responding to thalidomide. ( Burrows, NP; Davey, N; Hammond, AH; Jones, RR; Walport, MJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Navarro-Triviño, FJ | 1 |
| Ortego Centeno, N | 1 |
| Kindle, SA | 1 |
| Wetter, DA | 1 |
| Davis, MD | 1 |
| Pittelkow, MR | 1 |
| Sciallis, GF | 1 |
| Wienert, S | 1 |
| Gadola, S | 1 |
| Hunziker, T | 1 |
| Ordi, J | 1 |
| Cortes, F | 1 |
| Martinez, N | 1 |
| Mauri, M | 1 |
| De Torres, I | 1 |
| Vilardell, M | 1 |
| Burrows, NP | 1 |
| Walport, MJ | 1 |
| Hammond, AH | 1 |
| Davey, N | 1 |
| Jones, RR | 1 |
5 other studies available for thalidomide and Lupus Erythematosus Panniculitis
| Article | Year |
|---|---|
Linear lupus panniculitis of the scalp with good response to thalidomide.
Topics: Adult; Female; Humans; Immunosuppressive Agents; Panniculitis, Lupus Erythematosus; Scalp; Scalp Der | 2019 |
Lenalidomide treatment of cutaneous lupus erythematosus: the Mayo Clinic experience.
Topics: Academic Medical Centers; Adult; Age Factors; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Coho | 2016 |
Facets of lupus erythematosus: panniculitis responding to thalidomide.
Topics: Adolescent; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Panniculitis, Lupus E | 2008 |
Thalidomide induces amenorrhea in patients with lupus disease.
Topics: Adult; Amenorrhea; Female; Humans; Immunosuppressive Agents; Lupus Erythematosus, Discoid; Lupus Ery | 1998 |
Lupus erythematosus profundus with partial C4 deficiency responding to thalidomide.
Topics: Adolescent; Complement C4; Complement C4a; Complement C4b; Female; Humans; Panniculitis, Lupus Eryth | 1991 |