thalidomide has been researched along with Lung Injury, Acute in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Carfilzomib (Kyprolis™) is a new proteasome inhibitor that shows promise for the treatment of relapsing multiple myeloma." | 7.91 | Apremilast ameliorates carfilzomib-induced pulmonary inflammation and vascular injuries. ( Al-Harbi, MM; Al-Harbi, NO; Alanazi, AZ; Alhazzani, K; Aljerian, K; Alsanea, S; Belali, OM; Imam, F; Qamar, W, 2019) |
| "We studied the effect of thalidomide on NFκB-induced TNF-α in acute pancreatitis-associated lung injury in the rat." | 7.80 | Thalidomide alleviates acute pancreatitis-associated lung injury via down-regulation of NFκB induced TNF-α. ( Fan, LJ; Ji, SS; Li, HY; Li, W; Lv, P, 2014) |
| "To investigate the effects of thalidomide in a mouse model of paraquat-induced acute lung injury and the mechanisms underlying the properties of thalidomide." | 7.80 | [Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms]. ( Cai, X; Hong, G; Li, D; Li, M; Lu, Z; She, X; Wu, B; Zhao, G, 2014) |
| "To investigate the intervention effect of thalidomide on paraquat-induced acute lung injury in mice and its mechanism." | 7.79 | [Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms]. ( Chang, ZJ; Li, D; Lu, ZQ; Nan, C; Xu, LY; Zhao, GJ, 2013) |
| "Lenalidomide is now widely used for the treatment of multiple myeloma in virtue of its potent anti-tumor activity and low toxicity." | 7.79 | Lenalidomide-induced acute lung injury in case of multiple myeloma. ( Aoki, T; Danbara, M; Higashihara, M; Katayama, T; Miyazaki, K; Tadera, N; Togano, T, 2013) |
| " Carfilzomib (Kyprolis™) is a new proteasome inhibitor that shows promise for the treatment of relapsing multiple myeloma." | 3.91 | Apremilast ameliorates carfilzomib-induced pulmonary inflammation and vascular injuries. ( Al-Harbi, MM; Al-Harbi, NO; Alanazi, AZ; Alhazzani, K; Aljerian, K; Alsanea, S; Belali, OM; Imam, F; Qamar, W, 2019) |
| "To investigate the protective effect of thalidomide on acute lung injury (ALI) induced by paraquat (PQ) poisoning in rats and its possible mechanism." | 3.85 | [Protective effect of thalidomide on ALI induced by paraquat poisoning in rats and its mechanism]. ( Liu, T; Xie, Y; Xu, M; Zheng, F, 2017) |
| "We studied the effect of thalidomide on NFκB-induced TNF-α in acute pancreatitis-associated lung injury in the rat." | 3.80 | Thalidomide alleviates acute pancreatitis-associated lung injury via down-regulation of NFκB induced TNF-α. ( Fan, LJ; Ji, SS; Li, HY; Li, W; Lv, P, 2014) |
| "To investigate the effects of thalidomide in a mouse model of paraquat-induced acute lung injury and the mechanisms underlying the properties of thalidomide." | 3.80 | [Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms]. ( Cai, X; Hong, G; Li, D; Li, M; Lu, Z; She, X; Wu, B; Zhao, G, 2014) |
| "To investigate the intervention effect of thalidomide on paraquat-induced acute lung injury in mice and its mechanism." | 3.79 | [Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms]. ( Chang, ZJ; Li, D; Lu, ZQ; Nan, C; Xu, LY; Zhao, GJ, 2013) |
| "Lenalidomide is now widely used for the treatment of multiple myeloma in virtue of its potent anti-tumor activity and low toxicity." | 3.79 | Lenalidomide-induced acute lung injury in case of multiple myeloma. ( Aoki, T; Danbara, M; Higashihara, M; Katayama, T; Miyazaki, K; Tadera, N; Togano, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, T | 1 |
| Xie, Y | 1 |
| Xu, M | 1 |
| Zheng, F | 1 |
| Imam, F | 1 |
| Al-Harbi, NO | 1 |
| Al-Harbi, MM | 1 |
| Qamar, W | 1 |
| Aljerian, K | 1 |
| Belali, OM | 1 |
| Alsanea, S | 1 |
| Alanazi, AZ | 1 |
| Alhazzani, K | 1 |
| Li, D | 2 |
| Xu, LY | 1 |
| Chang, ZJ | 1 |
| Zhao, GJ | 1 |
| Nan, C | 1 |
| Lu, ZQ | 1 |
| Danbara, M | 1 |
| Tadera, N | 1 |
| Togano, T | 1 |
| Katayama, T | 1 |
| Aoki, T | 1 |
| Miyazaki, K | 1 |
| Higashihara, M | 1 |
| Lv, P | 1 |
| Li, HY | 1 |
| Ji, SS | 1 |
| Li, W | 1 |
| Fan, LJ | 1 |
| Zhao, G | 1 |
| Cai, X | 1 |
| She, X | 1 |
| Hong, G | 1 |
| Wu, B | 1 |
| Li, M | 1 |
| Lu, Z | 1 |
6 other studies available for thalidomide and Lung Injury, Acute
| Article | Year |
|---|---|
[Protective effect of thalidomide on ALI induced by paraquat poisoning in rats and its mechanism].
Topics: Acute Lung Injury; Animals; Lung; NF-kappa B; Paraquat; Rats; Rats, Sprague-Dawley; Rats, Wistar; Th | 2017 |
Apremilast ameliorates carfilzomib-induced pulmonary inflammation and vascular injuries.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Disease Models, Animal; | 2019 |
[Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms].
Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; NF-kapp | 2013 |
Lenalidomide-induced acute lung injury in case of multiple myeloma.
Topics: Acute Lung Injury; Antineoplastic Combined Chemotherapy Protocols; Humans; Lenalidomide; Male; Middl | 2013 |
Thalidomide alleviates acute pancreatitis-associated lung injury via down-regulation of NFκB induced TNF-α.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Down-Regulation; Immunosuppressive Agents; Lung; | 2014 |
[Effect of thalidomide in a mouse model of paraquat-induced acute lung injury and the underlying mechanisms].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Lung; Male; Malondialdehyde; Mice; Mice, Inbred | 2014 |