thalidomide has been researched along with Liver Failure, Acute in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reed-Guy, L | 1 |
| Hoteit, MA | 1 |
| Garfall, AL | 1 |
| Jain, P | 1 |
| Hamadani, M | 1 |
| Benson, DM | 1 |
| Copelan, EA | 1 |
| Liu, S | 1 |
| Zheng, M | 1 |
| Li, Z | 1 |
| Yu, Z | 1 |
| Lu, H | 1 |
1 review available for thalidomide and Liver Failure, Acute
| Article | Year |
|---|---|
Lenalidomide-induced acute liver failure.
Topics: Adenine; Aged, 80 and over; Antineoplastic Agents; Antiviral Agents; Hepatitis B, Chronic; Humans; L | 2009 |
3 other studies available for thalidomide and Liver Failure, Acute
| Article | Year |
|---|---|
Acute Liver Failure Associated With Pomalidomide Therapy for Multiple Myeloma.
Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Failure, Acute; Liver F | 2018 |
Thalidomide-induced fulminant hepatic failure.
Topics: Fatal Outcome; Female; Humans; Immunosuppressive Agents; Liver Failure, Acute; Middle Aged; Multiple | 2007 |
[The protective effects of thalidomide on acute liver failure].
Topics: Animals; Galactosamine; Immunosuppressive Agents; Lipopolysaccharides; Liver Failure, Acute; Male; R | 1999 |