thalidomide has been researched along with Lipodystrophy, Intestinal in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We concluded it was an immune reconstitution inflammatory syndrome (IRIS)." | 1.40 | A severe Whipple disease with an immune reconstitution inflammatory syndrome: an additional case of thalidomide efficiency. ( Lagier, JC; Le Blay, P; Pers, YM; Puechal, X; Rakotonirainy, H; Raoult, D, 2014) |
| "Immune reconstitution inflammatory syndrome was suspected, but corticosteroid therapy failed to improve the patient." | 1.36 | Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide. ( Fenollar, F; Lagier, JC; Lepidi, H; Liozon, E; Raoult, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Le Blay, P | 1 |
| Rakotonirainy, H | 1 |
| Lagier, JC | 2 |
| Raoult, D | 2 |
| Puechal, X | 1 |
| Pers, YM | 1 |
| Fenollar, F | 1 |
| Lepidi, H | 1 |
| Liozon, E | 1 |
2 other studies available for thalidomide and Lipodystrophy, Intestinal
| Article | Year |
|---|---|
A severe Whipple disease with an immune reconstitution inflammatory syndrome: an additional case of thalidomide efficiency.
Topics: Adult; Humans; Immune Reconstitution Inflammatory Syndrome; Immunosuppressive Agents; Male; Thalidom | 2014 |
Successful treatment of immune reconstitution inflammatory syndrome in Whipple's disease using thalidomide.
Topics: Humans; Immune Reconstitution Inflammatory Syndrome; Immunosuppressive Agents; Male; Middle Aged; Th | 2010 |