thalidomide has been researched along with Leukemia, T-Cell in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Leukemia, T-Cell: A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramsay, AG | 1 |
| Gribben, JG | 1 |
| Ezell, TN | 1 |
| Maloney, N | 1 |
| Githua, JW | 1 |
| Taylor, LD | 1 |
1 review available for thalidomide and Leukemia, T-Cell
| Article | Year |
|---|---|
Immune dysfunction in chronic lymphocytic leukemia T cells and lenalidomide as an immunomodulatory drug.
Topics: Antineoplastic Agents; Chronic Disease; Humans; Immunologic Factors; Lenalidomide; Leukemia, T-Cell; | 2009 |
1 other study available for thalidomide and Leukemia, T-Cell
| Article | Year |
|---|---|
Exposure to the anti-TNF-alpha drug thalidomide induces apoptotic cell death in human T leukemic cells.
Topics: Caspase 3; Caspases; Cell Death; Humans; Immunosuppressive Agents; Leukemia, T-Cell; Leukocytes, Mon | 2003 |