thalidomide has been researched along with Leukemia, Hairy Cell in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Leukemia, Hairy Cell: A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of hairy or flagellated cells in the blood and bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide was started at a daily dose of 100 mg/d and increased to 400 mg/d." | 5.33 | Hairy cell leukemia (HCL) with extensive myelofibrosis responds to thalidomide. ( Fenk, R; Gattermann, N; Germing, U; Haas, R; Kündgen, A; Strupp, C, 2005) |
| "Thalidomide was started at a daily dose of 100 mg/d and increased to 400 mg/d." | 1.33 | Hairy cell leukemia (HCL) with extensive myelofibrosis responds to thalidomide. ( Fenk, R; Gattermann, N; Germing, U; Haas, R; Kündgen, A; Strupp, C, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hanbali, A | 1 |
| Alrajeh, A | 1 |
| Rasheed, W | 1 |
| Strupp, C | 1 |
| Fenk, R | 1 |
| Kündgen, A | 1 |
| Gattermann, N | 1 |
| Haas, R | 1 |
| Germing, U | 1 |
| D'Orazio, AI | 1 |
3 other studies available for thalidomide and Leukemia, Hairy Cell
| Article | Year |
|---|---|
Plasma cell leukemia mimicking hairy cell leukemia.
Topics: Adult; Antineoplastic Agents; Bone Marrow; Bone Marrow Transplantation; Bortezomib; Cyclophosphamide | 2015 |
Hairy cell leukemia (HCL) with extensive myelofibrosis responds to thalidomide.
Topics: Aged; Cladribine; Humans; Leukemia, Hairy Cell; Male; Primary Myelofibrosis; Remission Induction; Th | 2005 |
37th Annual American Society of Clinical Oncology Meeting. San Francisco, CA. May 12-15, 2001.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD; Antigens, Differentiat | 2001 |