thalidomide has been researched along with Leptospirosis in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Leptospirosis: Infections with bacteria of the genus LEPTOSPIRA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide had minimal impact on survival in the late treatment of leptospirosis hamster model." | 7.80 | Immunomodulatory treatment with thalidomide in experimental leptospirosis in Golden Syrian hamsters (Mesocricetus auratus). ( Athanazio, DA; de Azevedo, EC; dos Reis, MG; dos Santos, AC; Macedo, JO; Sampaio, Mde Q; Santos, CS; Soares, LM, 2014) |
| "Thalidomide had minimal impact on survival in the late treatment of leptospirosis hamster model." | 3.80 | Immunomodulatory treatment with thalidomide in experimental leptospirosis in Golden Syrian hamsters (Mesocricetus auratus). ( Athanazio, DA; de Azevedo, EC; dos Reis, MG; dos Santos, AC; Macedo, JO; Sampaio, Mde Q; Santos, CS; Soares, LM, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soares, LM | 1 |
| Macedo, JO | 1 |
| de Azevedo, EC | 1 |
| Santos, CS | 1 |
| Sampaio, Mde Q | 1 |
| dos Santos, AC | 1 |
| dos Reis, MG | 1 |
| Athanazio, DA | 1 |
1 other study available for thalidomide and Leptospirosis
| Article | Year |
|---|---|
Immunomodulatory treatment with thalidomide in experimental leptospirosis in Golden Syrian hamsters (Mesocricetus auratus).
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Cricetinae; Disease Models, Animal; Drug Therapy, Combin | 2014 |