thalidomide has been researched along with Leg Ulcer in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Wang, Z | 1 |
| Zhao, Y | 1 |
| Luo, Y | 1 |
| Xu, W | 1 |
| Marion, TN | 1 |
| Liu, Y | 1 |
| Salas-Espíndola, Y | 1 |
| Peniche-Castellanos, A | 1 |
| López-Gehrke, I | 1 |
| Mercadillo-Pérez, P | 1 |
| Rose, AE | 1 |
| Patel, U | 1 |
| Chu, J | 1 |
| Patel, R | 1 |
| Meehan, S | 1 |
| Latkowski, JA | 1 |
| Prigent, F | 1 |
| Ouazzani, W | 1 |
| Rustin, MH | 1 |
| Gilkes, JJ | 1 |
| Robinson, TW | 1 |
1 review available for thalidomide and Leg Ulcer
| Article | Year |
|---|---|
Erythrodermic lichen planus.
Topics: Aged; Chills; Dermatitis, Exfoliative; Glucocorticoids; Humans; Immunologic Factors; Itraconazole; L | 2011 |
4 other studies available for thalidomide and Leg Ulcer
| Article | Year |
|---|---|
Successful mesenchymal stem cell treatment of leg ulcers complicated by Behcet disease: A case report and literature review.
Topics: Adalimumab; Behcet Syndrome; Dose-Response Relationship, Drug; Drug Resistance; Drug Substitution; E | 2018 |
[Leukocytoclastic vasculitis related to cocaine use].
Topics: Adrenal Cortex Hormones; Antibodies, Antineutrophil Cytoplasmic; Cocaine; Cocaine-Related Disorders; | 2011 |
[Cutaneous sarcoidosis. Treatment with thalidomide].
Topics: Humans; Leg Ulcer; Sarcoidosis; Thalidomide | 1983 |
Pyoderma gangrenosum associated with Behçet's disease: treatment with thalidomide.
Topics: Adult; Behcet Syndrome; Gangrene; Humans; Leg Ulcer; Male; Prednisolone; Pyoderma; Recurrence; Thali | 1990 |