Page last updated: 2024-11-05

thalidomide and Keratitis

thalidomide has been researched along with Keratitis in 1 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Keratitis: Inflammation of the cornea.

Research Excerpts

ExcerptRelevanceReference
"Evaluate the effect of LASSBio-596, structurally designed as a new hybrid of thalidomide, on inflammatory corneal angiogenesis."7.78Potential inhibitory effect of LASSBio-596, a new thalidomide hybrid, on inflammatory corneal angiogenesis in rabbits. ( Amaral de Moraes, ME; Barreiro, EJ; Lima, LM; Odorico de Moraes, M; Ribeiro, JC; Ribeiro, MZ; Ricardo, NM; Vagnaldo Fechine, F, 2012)
"Evaluate the effect of LASSBio-596, structurally designed as a new hybrid of thalidomide, on inflammatory corneal angiogenesis."3.78Potential inhibitory effect of LASSBio-596, a new thalidomide hybrid, on inflammatory corneal angiogenesis in rabbits. ( Amaral de Moraes, ME; Barreiro, EJ; Lima, LM; Odorico de Moraes, M; Ribeiro, JC; Ribeiro, MZ; Ricardo, NM; Vagnaldo Fechine, F, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ribeiro, JC1
Vagnaldo Fechine, F1
Ribeiro, MZ1
Barreiro, EJ1
Lima, LM1
Ricardo, NM1
Amaral de Moraes, ME1
Odorico de Moraes, M1

Other Studies

1 other study available for thalidomide and Keratitis

ArticleYear
Potential inhibitory effect of LASSBio-596, a new thalidomide hybrid, on inflammatory corneal angiogenesis in rabbits.
    Ophthalmic research, 2012, Volume: 48, Issue:4

    Topics: Animals; Corneal Neovascularization; Dexamethasone; Disease Models, Animal; Glucocorticoids; Keratit

2012