thalidomide has been researched along with Jaundice in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The chemotherapeutic regimen melphalan, prednisolone, and thalidomide (MPT) is the standard of care for symptomatic multiple myeloma patients who are not eligible for high dose chemotherapy followed by autologous stem cell therapy." | 7.78 | Lenalidomide induced intrahepatic cholestasis in newly diagnosed patients of multiple myeloma. ( Jena, RK; Kansurkar, SS; Swain, M; Swain, TR, 2012) |
| "The chemotherapeutic regimen melphalan, prednisolone, and thalidomide (MPT) is the standard of care for symptomatic multiple myeloma patients who are not eligible for high dose chemotherapy followed by autologous stem cell therapy." | 3.78 | Lenalidomide induced intrahepatic cholestasis in newly diagnosed patients of multiple myeloma. ( Jena, RK; Kansurkar, SS; Swain, M; Swain, TR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jena, RK | 1 |
| Swain, TR | 1 |
| Kansurkar, SS | 1 |
| Swain, M | 1 |
1 other study available for thalidomide and Jaundice
| Article | Year |
|---|---|
Lenalidomide induced intrahepatic cholestasis in newly diagnosed patients of multiple myeloma.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cholestasis, Intrahepa | 2012 |