thalidomide has been researched along with Intraventricular Septal Defects in 6 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The cats were given daily oral doses of thalidomide as follows: 10 mg/kg on days 10-20 of pregnancy, 240 mg/kg on days 10-14, and 120, 240, and 480 mg/kg on days 15-17 or 18-20 of pregnancy." | 3.65 | Fetal cardiovascular and other defects induced by thalidomide in cats. ( Khera, KS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SCHUMACHER, H | 1 |
| ODUNJO, F | 1 |
| Khera, KS | 1 |
| Nora, JJ | 1 |
| Nora, AH | 1 |
| Gilani, SH | 1 |
| Simcha, A | 1 |
| Vickers, TH | 1 |
1 review available for thalidomide and Intraventricular Septal Defects
| Article | Year |
|---|---|
The evolution of specific genetic and environmental counseling in congenital heart diseases.
Topics: Chromosomes; Counseling; Ductus Arteriosus, Patent; Environmental Health; Heart Defects, Congenital; | 1978 |
5 other studies available for thalidomide and Intraventricular Septal Defects
| Article | Year |
|---|---|
[PERSISTENT TRUNCUS ARTERIOSUS COMMUNIS IN SO-CALLED THALIDOMIDE EMBRYOPATHY].
Topics: Ductus Arteriosus; Ectromelia; Fetal Diseases; Heart Septal Defects; Heart Septal Defects, Ventricul | 1963 |
Fetal cardiovascular and other defects induced by thalidomide in cats.
Topics: Animals; Cardiomegaly; Cats; Coronary Vessels; Female; Fetal Heart; Heart Atria; Heart Defects, Cong | 1975 |
Cardiovascular malformations in the chick embryo induced by thalidomide.
Topics: Abnormalities, Drug-Induced; Animals; Aortic Arch Syndromes; Aortic Valve Stenosis; Cardiovascular A | 1973 |
Congenital heart disease in radial clubbed hand syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Hand Deformities, Acquired; Heart Defe | 1971 |
The cardiovascular malformations in the rabbit thalidomide embryopathy.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Bronchial Arteries; Cardiovascular Abnormalities; Cardi | 1968 |