thalidomide has been researched along with Intestinal Perforation in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In conclusion, GI perforation in AL amyloidosis is rare and mostly reported after treatment initiation." | 2.58 | Gastrointestinal perforation in light chain amyloidosis in the era of novel agent therapy - a case series and review of the literature. ( Avivi, I; Cohen, Y; Duek, A; Gatt, ME; Leiba, M; Shaulov, A, 2018) |
| "Thalidomide 100 mg/day was then started, and the symptoms disappeared within 2 weeks." | 1.32 | Treatment of recurrent perforating intestinal ulcers with thalidomide in Behçet's disease. ( Arslanturk, H; Bayram, I; Gul, A; Kotan, MC; Sayarlioglu, M; Topcu, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shaulov, A | 1 |
| Avivi, I | 1 |
| Cohen, Y | 1 |
| Duek, A | 1 |
| Leiba, M | 1 |
| Gatt, ME | 1 |
| Sriskandarajah, P | 1 |
| Scott, F | 1 |
| Muthalali, S | 1 |
| Mercieca, J | 1 |
| Ramos, JM | 1 |
| Masiá, M | 1 |
| Durán, R | 1 |
| Gutiérrez, F | 1 |
| Sayarlioglu, M | 1 |
| Kotan, MC | 1 |
| Topcu, N | 1 |
| Bayram, I | 1 |
| Arslanturk, H | 1 |
| Gul, A | 1 |
| McClay, H | 1 |
| Cervi, P | 1 |
1 review available for thalidomide and Intestinal Perforation
| Article | Year |
|---|---|
Gastrointestinal perforation in light chain amyloidosis in the era of novel agent therapy - a case series and review of the literature.
Topics: Adult; Aged; Bortezomib; Humans; Immunoglobulin Light-chain Amyloidosis; Intestinal Perforation; Len | 2018 |
4 other studies available for thalidomide and Intestinal Perforation
| Article | Year |
|---|---|
Life-threatening bowel perforation while on thalidomide-based triplet regimen for multiple myeloma: a retrospective case series.
Topics: Aged; Aged, 80 and over; Diverticulitis; Female; Humans; Intestinal Perforation; Male; Middle Aged; | 2016 |
Idiopathic ileocolitis with perforation associated with HIV infection: thalidomide treatment.
Topics: Adult; Crohn Disease; HIV Infections; Humans; Immunosuppressive Agents; Intestinal Perforation; Male | 2012 |
Treatment of recurrent perforating intestinal ulcers with thalidomide in Behçet's disease.
Topics: Adjuvants, Immunologic; Adult; Behcet Syndrome; Female; Humans; Intestinal Perforation; Recurrence; | 2004 |
Thalidomide and bowel perforation: four cases in one hospital.
Topics: Adult; Aged; Angiogenesis Inhibitors; Colonic Diseases; Female; Humans; Ileal Diseases; Intestinal P | 2008 |