thalidomide has been researched along with Infections, Microspora in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide is an experimental drug currently used for oral aphthous ulcers and wasting syndrome, and is the same drug associated with severe fetal abnormalities in the 1960s." | 5.30 | Thalidomide shows benefit for microsporidial diarrhea. ( Bartnof, HS, 1997) |
| "Eighteen subjects with chronic diarrhea caused by Enterocytozoon bieneusi that had not responded symptomatically to albendazole and 1 untreated subject with Encephalitozoon intestinalis received 1 month of thalidomide, 100 mg nocte." | 5.08 | Thalidomide: a novel therapy for microsporidiosis. ( Barrett, M; Ellis, D; Francis, N; Gazzard, B; Rowbottom, A; Sharpstone, D; Tovey, G, 1997) |
| "Thalidomide is an experimental drug currently used for oral aphthous ulcers and wasting syndrome, and is the same drug associated with severe fetal abnormalities in the 1960s." | 1.30 | Thalidomide shows benefit for microsporidial diarrhea. ( Bartnof, HS, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharpstone, D | 2 |
| Rowbottom, A | 2 |
| Nelson, M | 1 |
| Gazzard, B | 2 |
| Francis, N | 1 |
| Tovey, G | 1 |
| Ellis, D | 1 |
| Barrett, M | 1 |
| Surawicz, CM | 2 |
| Bartnof, HS | 1 |
1 trial available for thalidomide and Infections, Microspora
| Article | Year |
|---|---|
Thalidomide: a novel therapy for microsporidiosis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Diarrhea; Female; Humans; Male; Microsporidiosis | 1997 |
4 other studies available for thalidomide and Infections, Microspora
| Article | Year |
|---|---|
The treatment of microsporidial diarrhoea with thalidomide.
Topics: AIDS-Related Opportunistic Infections; Animals; Diarrhea; Humans; Male; Microsporida; Microsporidios | 1995 |
Thalidomide for AIDS diarrhea?
Topics: AIDS-Related Opportunistic Infections; Animals; Antiprotozoal Agents; Diarrhea; Humans; Microsporida | 1997 |
New hope for AIDS patients.
Topics: AIDS-Related Opportunistic Infections; Animals; Humans; Intestinal Diseases, Parasitic; Microsporida | 1998 |
Thalidomide shows benefit for microsporidial diarrhea.
Topics: Antiprotozoal Agents; Clinical Trials as Topic; Diarrhea; HIV Infections; Microsporidiosis; Thalidom | 1997 |