thalidomide has been researched along with Infection, Postoperative Wound in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide treated rats had lower TNF levels at all time points (P = <0." | 1.29 | Thalidomide inhibits TNF response and increases survival following endotoxin injection in rats. ( Condon, M; Hsieh, J; Murphy, T; Rush, B; Schmidt, H; Simonian, G, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, H | 1 |
| Rush, B | 1 |
| Simonian, G | 1 |
| Murphy, T | 1 |
| Hsieh, J | 1 |
| Condon, M | 1 |
1 other study available for thalidomide and Infection, Postoperative Wound
| Article | Year |
|---|---|
Thalidomide inhibits TNF response and increases survival following endotoxin injection in rats.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Lipop | 1996 |