thalidomide has been researched along with Ileal Diseases in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Ileal Diseases: Pathological development in the ILEUM including the ILEOCECAL VALVE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of intractable Crohn's disease unresponsive to all forms of therapy, including multiple operations and medication, is reported." | 1.32 | Disappearance of Crohn's ulcers in the terminal ileum after thalidomide therapy. ( Hershfield, NB, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miranda-Bautista, J | 1 |
| Fernández-Simón, A | 1 |
| Pérez-Sánchez, I | 1 |
| Menchén, L | 1 |
| Hershfield, NB | 1 |
| Cohen, LB | 1 |
| McClay, H | 1 |
| Cervi, P | 1 |
4 other studies available for thalidomide and Ileal Diseases
| Article | Year |
|---|---|
Weber-Christian disease with ileocolonic involvement successfully treated with infliximab.
Topics: Adult; Anti-Infective Agents; Biopsy; Colonic Diseases; Female; Humans; Ileal Diseases; Infliximab; | 2015 |
Disappearance of Crohn's ulcers in the terminal ileum after thalidomide therapy.
Topics: Adult; Colonoscopy; Contraindications; Crohn Disease; Humans; Ileal Diseases; Immunosuppressive Agen | 2004 |
Re: Disappearance of Crohn's ulcers in the terminal ileum after thalidomide therapy. Can J Gastroenterol 2004; 18(2): 101-104.
Topics: Crohn Disease; Humans; Ileal Diseases; Immunosuppressive Agents; Thalidomide; Treatment Outcome; Tum | 2004 |
Thalidomide and bowel perforation: four cases in one hospital.
Topics: Adult; Aged; Angiogenesis Inhibitors; Colonic Diseases; Female; Humans; Ileal Diseases; Intestinal P | 2008 |