thalidomide has been researched along with Hypokalemia in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " On arrival, laboratory test results were significant for hypokalemia, hyperchloremic metabolic acidosis, low uric acid concentration, positive urine anion gap, and proteinuria, which resolved on discontinuation of the drug." | 7.85 | Proximal Renal Tubular Acidosis (Fanconi Syndrome) Induced by Apremilast: A Case Report. ( Afridi, F; Kar, P; King-Morris, K; Komarla, A; Perrone, D, 2017) |
| " On arrival, laboratory test results were significant for hypokalemia, hyperchloremic metabolic acidosis, low uric acid concentration, positive urine anion gap, and proteinuria, which resolved on discontinuation of the drug." | 3.85 | Proximal Renal Tubular Acidosis (Fanconi Syndrome) Induced by Apremilast: A Case Report. ( Afridi, F; Kar, P; King-Morris, K; Komarla, A; Perrone, D, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perrone, D | 1 |
| Afridi, F | 1 |
| King-Morris, K | 1 |
| Komarla, A | 1 |
| Kar, P | 1 |
1 other study available for thalidomide and Hypokalemia
| Article | Year |
|---|---|
Proximal Renal Tubular Acidosis (Fanconi Syndrome) Induced by Apremilast: A Case Report.
Topics: Acidosis; Acidosis, Renal Tubular; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Psoriat | 2017 |