thalidomide has been researched along with Hypogonadism in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-five patients with newly diagnosed POEMS syndrome were treated with Lenalidomide (10 mg daily for 21 days) and dexamethasone (40 mg once per week) for 12 cycles." | 7.83 | Improvement of sexual function in POEMS syndrome after combination therapy of Lenalidomide and dexamethasone. ( Cai, Q; Cao, X; Huang, X; Li, J; Wang, C; Yang, H; Zhou, D, 2016) |
| "Thirty-five patients with newly diagnosed POEMS syndrome were treated with Lenalidomide (10 mg daily for 21 days) and dexamethasone (40 mg once per week) for 12 cycles." | 3.83 | Improvement of sexual function in POEMS syndrome after combination therapy of Lenalidomide and dexamethasone. ( Cai, Q; Cao, X; Huang, X; Li, J; Wang, C; Yang, H; Zhou, D, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaidi, S | 1 |
| Sattar, S | 1 |
| Asumal, KB | 1 |
| Yang, H | 1 |
| Huang, X | 1 |
| Cai, Q | 1 |
| Wang, C | 1 |
| Cao, X | 1 |
| Zhou, D | 1 |
| Li, J | 1 |
2 other studies available for thalidomide and Hypogonadism
| Article | Year |
|---|---|
An Adult with Polyneuropathy and Hypogonadism due to Poems Syndrome.
Topics: Adult; Dexamethasone; Female; Humans; Hypogonadism; Melphalan; Paraproteinemias; POEMS Syndrome; Pol | 2017 |
Improvement of sexual function in POEMS syndrome after combination therapy of Lenalidomide and dexamethasone.
Topics: Adult; Aged; Dexamethasone; Female; Humans; Hypogonadism; Immunologic Factors; Lenalidomide; Male; M | 2016 |