thalidomide has been researched along with Hypertrophy in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a retrospective study of 832 cases of thalidomide embryopathy (ThE) between October 1, 1959 and July 31, 1962, a highly significant accumulation of cases with infantile hypertrophic pyloric stenosis (IHPS) was registrated." | 7.67 | Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide. ( Kramer, M; Schäfer, KH, 1987) |
| "In a retrospective study of 832 cases of thalidomide embryopathy (ThE) between October 1, 1959 and July 31, 1962, a highly significant accumulation of cases with infantile hypertrophic pyloric stenosis (IHPS) was registrated." | 3.67 | Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide. ( Kramer, M; Schäfer, KH, 1987) |
| "Hypertrophic genital herpes is a disfiguring manifestation of a common infection seen in immunocompromised hosts that can be clinically mistaken for malignancy." | 2.44 | Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals. ( Bergin, C; Holmes, A; McMenamin, M; Mulcahy, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Holmes, A | 1 |
| McMenamin, M | 1 |
| Mulcahy, F | 1 |
| Bergin, C | 1 |
| Schäfer, KH | 1 |
| Kramer, M | 1 |
1 review available for thalidomide and Hypertrophy
| Article | Year |
|---|---|
Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals.
Topics: Adult; Genitalia, Male; Herpes Genitalis; HIV Infections; Humans; Hypertrophy; Immunosuppressive Age | 2007 |
1 other study available for thalidomide and Hypertrophy
| Article | Year |
|---|---|
Infantile hypertrophic pyloric stenosis after prenatal exposure to thalidomide.
Topics: Female; Germany, West; Humans; Hypertrophy; Infant, Newborn; Male; Pyloric Stenosis; Retrospective S | 1987 |