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thalidomide and Herpes Simplex Virus Infection

thalidomide has been researched along with Herpes Simplex Virus Infection in 8 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
" We present a case of coinfection with disseminated HSV and VZV infection in a patient taking thalidomide for relapsed multiple myeloma."7.71Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma. ( Curley, MJ; Hassoun, PM; Hussein, SA, 2002)
" We present a case of coinfection with disseminated HSV and VZV infection in a patient taking thalidomide for relapsed multiple myeloma."3.71Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma. ( Curley, MJ; Hassoun, PM; Hussein, SA, 2002)
" Thalidomide (Synovir), developed by Celgene, has received limited approval for the treatment of leprosy."3.70FDA approves fomivirsen, famciclovir, and Thalidomide. Food and Drug Administration. ( Highleyman, L, 1998)
"Recognition and timely adequate treatment of erythema multiforme remain a major challenge."2.58Current Perspectives on Erythema Multiforme. ( Harr, T; Lerch, M; Mainetti, C; Terziroli Beretta-Piccoli, B, 2018)
"In thalidomide-treated mice, TNF-alpha RNA levels were reduced in the SCN."1.33Tumor necrosis factor alpha and macrophages in the brain of herpes simplex virus type 1-infected BALB/c mice. ( Atherton, SS; Fields, M; Zhang, M; Zheng, M, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lerch, M1
Mainetti, C1
Terziroli Beretta-Piccoli, B1
Harr, T1
König, C1
Kleber, M1
Reinhardt, H1
Knop, S1
Wäsch, R1
Engelhardt, M1
Aslam, A1
Chalmers, R1
Sohn, S2
Lee, ES2
Lee, SI1
Kim, YA2
Kwon, HJ2
Bang, D2
Lee, S2
Fields, M1
Zheng, M1
Zhang, M1
Atherton, SS1
Highleyman, L1
Curley, MJ1
Hussein, SA1
Hassoun, PM1

Reviews

1 review available for thalidomide and Herpes Simplex Virus Infection

ArticleYear
Current Perspectives on Erythema Multiforme.
    Clinical reviews in allergy & immunology, 2018, Volume: 54, Issue:1

    Topics: Acyclovir; Dapsone; Drug-Related Side Effects and Adverse Reactions; Erythema Multiforme; Herpes Sim

2018

Other Studies

7 other studies available for thalidomide and Herpes Simplex Virus Infection

ArticleYear
Incidence, risk factors, and implemented prophylaxis of varicella zoster virus infection, including complicated varicella zoster virus and herpes simplex virus infections, in lenalidomide-treated multiple myeloma patients.
    Annals of hematology, 2014, Volume: 93, Issue:3

    Topics: Acyclovir; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibiotic Prophylaxis; Antiviral Agent

2014
Mucocutaneous ulceration in a previously healthy man.
    The Journal of family practice, 2014, Volume: 63, Issue:2

    Topics: Adult; Behcet Syndrome; Crohn Disease; Diagnosis, Differential; Erythema Multiforme; Herpes Simplex;

2014
Therapeutic effect of thalidomide through cytokine and chemokine regulation in herpes simplex virus-induced Behçet's disease-like animal model.
    Advances in experimental medicine and biology, 2003, Volume: 528

    Topics: Animals; Behcet Syndrome; Chemokine CCL4; Chemokines; Cytokines; Disease Models, Animal; Gene Expres

2003
Thalidomide upregulates macrophage inflammatory protein-1alpha in a herpes simplex virus-induced Behçet's disease-like animal model.
    Archives of dermatological research, 2004, Volume: 296, Issue:4

    Topics: Animals; Apoptosis; Behcet Syndrome; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Disease Models

2004
Tumor necrosis factor alpha and macrophages in the brain of herpes simplex virus type 1-infected BALB/c mice.
    Journal of neurovirology, 2006, Volume: 12, Issue:6

    Topics: Animals; Brain; Clodronic Acid; Female; Flow Cytometry; Fluorescent Antibody Technique; Herpes Simpl

2006
FDA approves fomivirsen, famciclovir, and Thalidomide. Food and Drug Administration.
    BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1998

    Topics: 2-Aminopurine; AIDS-Related Opportunistic Infections; Antiviral Agents; Cytomegalovirus Retinitis; D

1998
Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma.
    Journal of clinical microbiology, 2002, Volume: 40, Issue:6

    Topics: Angiogenesis Inhibitors; Female; Herpes Simplex; Herpes Zoster; Humans; Middle Aged; Multiple Myelom

2002