thalidomide has been researched along with Hernia, Umbilical in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Hernia, Umbilical: A HERNIA due to an imperfect closure or weakness of the umbilical ring. It appears as a skin-covered protrusion at the UMBILICUS during crying, coughing, or straining. The hernia generally consists of OMENTUM or SMALL INTESTINE. The vast majority of umbilical hernias are congenital but can be acquired due to severe abdominal distention.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (75.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
MATTURRI, L | 1 |
NODARI, R | 1 |
Parman, T | 1 |
Wiley, MJ | 1 |
Wells, PG | 1 |
Paulsen, K | 1 |
Bouckaert, JI | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
QUIREDEX: A National, Open-Label, Multicenter, Randomized, Phase III Study of Revlimid (Lenalidomide) and Dexamethasone (ReDex) Treatment Versus Observation in Patients With Smoldering Multiple Myeloma With High Risk of Progression[NCT00480363] | Phase 3 | 120 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 other studies available for thalidomide and Hernia, Umbilical
Article | Year |
---|---|
[ANATOMOCLINICAL STUDY OF 19 CASES OF EMBRYOPATHY CAUSED BY THALIDOMIDE].
Topics: Appendix; Congenital Abnormalities; Ectromelia; Female; Fetal Diseases; Heart Defects, Congenital; H | 1963 |
Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity.
Topics: Animals; Cyclic N-Oxides; DNA Damage; Drug Resistance; Embryo Loss; Embryo, Mammalian; Female; Free | 1999 |
Otological features in exomphalos-macro-glossia-gigantism syndrome (Wiedemann's syndrome).
Topics: Abnormalities, Drug-Induced; Adolescent; Audiometry; Deafness; Female; Gigantism; Hernia, Umbilical; | 1973 |
[The first description of the Widemann-Beckwith syndrome?].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adrenal Gland Diseases; Endocrinology; Hernia, | 1971 |