Page last updated: 2024-11-05

thalidomide and Hepatitis

thalidomide has been researched along with Hepatitis in 5 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Childhood tuberculous meningitis is associated with serious long-term sequelae, including mental retardation, behavior disturbances, and motor handicap."2.71Adjunctive thalidomide therapy for childhood tuberculous meningitis: results of a randomized study. ( Hanekom, WA; Haslett, PA; Kaplan, G; Schoeman, JF; Springer, P; Swanevelder, S; van Rensburg, AJ, 2004)
"Thalidomide-treated group was given thalidomide (10mg/kg/day) intraperitoneally for 10 consecutive days."1.32Thalidomide salvages lethal hepatic necroinflammation and accelerates recovery from cirrhosis in rats. ( Chen, MF; Ho, YP; Huang, SF; Jan, YY; Yeh, JN; Yeh, TS, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HEINE, W1
KIRCHMAIR, H1
FIEDLER, M1
STUEWE, W1
Schoeman, JF1
Springer, P1
van Rensburg, AJ1
Swanevelder, S1
Hanekom, WA1
Haslett, PA1
Kaplan, G1
Yeh, TS1
Ho, YP1
Huang, SF1
Yeh, JN1
Jan, YY1
Chen, MF1
Jörgensen, G1
Schönenberg, H1

Trials

1 trial available for thalidomide and Hepatitis

ArticleYear
Adjunctive thalidomide therapy for childhood tuberculous meningitis: results of a randomized study.
    Journal of child neurology, 2004, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antitubercular Agents; Chemotherapy, Adjuvant; Ch

2004

Other Studies

4 other studies available for thalidomide and Hepatitis

ArticleYear
[THALIDOMIDE EMBRYOPATHY IN RABBITS FOLLOWING TRANSIENT LIVER DAMAGE IN THE MOTHER BY CARBON TETRACHLORIDE].
    Klinische Wochenschrift, 1964, Jun-15, Volume: 42

    Topics: Abnormalities, Drug-Induced; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical

1964
Thalidomide salvages lethal hepatic necroinflammation and accelerates recovery from cirrhosis in rats.
    Journal of hepatology, 2004, Volume: 41, Issue:4

    Topics: Animals; Collagenases; Hepatitis; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Male; Matrix

2004
[Malformations in otorhinolaryngology. Genetic report].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Chromosome Aberrations; Chromosome Diso

1972
[Malformation syndrome and urinary organs].
    Zeitschrift fur Urologie und Nephrologie, 1971, Volume: 64, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Child, Preschool; Chromosomes, Human, 1

1971