Page last updated: 2024-11-05

thalidomide and Hemangioendothelioma, Epithelioid

thalidomide has been researched along with Hemangioendothelioma, Epithelioid in 6 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Hemangioendothelioma, Epithelioid: A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have borderline aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
" Although treatment was initiated with thalidomide, the patient developed multiple organ dysfunction syndrome (MODS) and succumbed to his disease."3.73Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon. ( Bölke, E; Budach, W; Gripp, S; Orth, K; Peiper, M; Reinecke, P; Schwarz, A; van de Nes, JA, 2006)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pallotti, MC1
Nannini, M1
Agostinelli, C1
Leoni, S1
Scioscio, VD1
Mandrioli, A1
Lolli, C1
Saponara, M1
Pileri, S1
Bolondi, L1
Biasco, G1
Pantaleo, MA1
Gurung, S1
Fu, H1
Zhang, WW1
Gu, YH1
Kassam, A1
Mandel, K1
Sumrall, A1
Fredericks, R1
Berthold, A1
Shumaker, G1
Mascarenhas, RC1
Sanghvi, AN1
Friedlander, L1
Geyer, SJ1
Beasley, HS1
Van Thiel, DH1
Bölke, E1
Gripp, S1
Peiper, M1
Budach, W1
Schwarz, A1
Orth, K1
Reinecke, P1
van de Nes, JA1

Reviews

1 review available for thalidomide and Hemangioendothelioma, Epithelioid

ArticleYear
Hepatic epithelioid hemangioendothelioma metastasized to the peritoneum, omentum and mesentery: a case report.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Diagnosis, Differential;

2015

Other Studies

5 other studies available for thalidomide and Hemangioendothelioma, Epithelioid

ArticleYear
Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma.
    World journal of gastroenterology, 2014, Jun-14, Volume: 20, Issue:22

    Topics: Aged; Angiogenesis Inhibitors; Antigens, CD34; Biomarkers, Tumor; Biopsy; Hemangioendothelioma, Epit

2014
Metastatic hepatic epithelioid hemangioendothelioma in a teenage girl.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Ce

2008
Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease.
    Journal of neuro-oncology, 2010, Volume: 97, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Clinical Trials as Topic; Female; Hemangioendotheliom

2010
Thalidomide inhibits the growth and progression of hepatic epithelioid hemangioendothelioma.
    Oncology, 2004, Volume: 67, Issue:5-6

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Disease Progression; Drug Administration Schedule; H

2004
Multifocal epithelioid hemangioendothelioma: case report of a clinical chamaeleon.
    European journal of medical research, 2006, Nov-30, Volume: 11, Issue:11

    Topics: Angiogenesis Inhibitors; Diagnosis, Differential; Fatal Outcome; Hemangioendothelioma, Epithelioid;

2006