thalidomide has been researched along with Growth Disorders in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Growth Disorders: Deviations from the average values for a specific age and sex in any or all of the following: height, weight, skeletal proportions, osseous development, or maturation of features. Included here are both acceleration and retardation of growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proteus syndrome is an overgrowth syndrome caused by a somatic activating mutation in AKT1." | 2.61 | Vascular malformations syndromes: an update. ( Arias-Santiago, S; Martinez-Lopez, A; Molina-Leyva, A; Montero-Vilchez, T; Salvador-Rodriguez, L; Tercedor-Sanchez, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martinez-Lopez, A | 1 |
| Salvador-Rodriguez, L | 1 |
| Montero-Vilchez, T | 1 |
| Molina-Leyva, A | 1 |
| Tercedor-Sanchez, J | 1 |
| Arias-Santiago, S | 1 |
| Marchetti, F | 1 |
| Martelossi, S | 1 |
| Ventura, A | 1 |
| Shiono, H | 1 |
| Gressmann, C | 1 |
2 reviews available for thalidomide and Growth Disorders
| Article | Year |
|---|---|
Vascular malformations syndromes: an update.
Topics: Abnormalities, Multiple; Bevacizumab; Class I Phosphatidylinositol 3-Kinases; Growth Disorders; Huma | 2019 |
[Diseases and dermatoglyphics].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Bone and Bones; Chromosome Aberrations; Chromo | 1970 |
2 other studies available for thalidomide and Growth Disorders
| Article | Year |
|---|---|
Inflammatory bowel disease.
Topics: Child; Crohn Disease; Enteral Nutrition; Growth Disorders; Humans; Immunosuppressive Agents; Thalido | 2002 |
[Growth in length of children damaged through thalidomide (author's transl)].
Topics: Abnormalities, Drug-Induced; Age Factors; Anthropometry; Arm; Body Height; Child; Child, Preschool; | 1974 |