Page last updated: 2024-11-05

thalidomide and Granuloma Annulare

thalidomide has been researched along with Granuloma Annulare in 3 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Granuloma Annulare: Benign granulomatous disease of unknown etiology characterized by a ring of localized or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures.

Research Excerpts

ExcerptRelevanceReference
" We present a 75-year-old Caucasian man with a violaceous ring-like firm, papular eruption, localized on the dorsal aspect of both hands, with histological features of GA, which subsequently resolved with the discontinuation of thalidomide he had started 1 month earlier for the treatment of a multiple myeloma."7.80Thalidomide-induced granuloma annulare. ( Atzori, L; Caddori, A; Ferreli, C; Manunza, F; Pau, M, 2014)
" We present a 75-year-old Caucasian man with a violaceous ring-like firm, papular eruption, localized on the dorsal aspect of both hands, with histological features of GA, which subsequently resolved with the discontinuation of thalidomide he had started 1 month earlier for the treatment of a multiple myeloma."3.80Thalidomide-induced granuloma annulare. ( Atzori, L; Caddori, A; Ferreli, C; Manunza, F; Pau, M, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Joshi, TP1
Duvic, M1
Hansel, K1
Biondi, F1
Bianchi, L1
Tramontana, M1
Marietti, R1
Stingeni, L1
Ferreli, C1
Atzori, L1
Manunza, F1
Pau, M1
Caddori, A1

Reviews

2 reviews available for thalidomide and Granuloma Annulare

ArticleYear
Granuloma Annulare: An Updated Review of Epidemiology, Pathogenesis, and Treatment Options.
    American journal of clinical dermatology, 2022, Volume: 23, Issue:1

    Topics: Anti-Infective Agents; Antimalarials; Biological Therapy; Comorbidity; Dermatologic Agents; Diabetes

2022
Generalized granuloma annulare successfully treated with apremilast: report of two cases and literature review.
    Clinical and experimental dermatology, 2021, Volume: 46, Issue:8

    Topics: Adult; Aged; Female; Granuloma Annulare; Humans; Male; Middle Aged; Phosphodiesterase 4 Inhibitors;

2021

Other Studies

1 other study available for thalidomide and Granuloma Annulare

ArticleYear
Thalidomide-induced granuloma annulare.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:3

    Topics: Aged; Granuloma Annulare; Hand; Humans; Immunosuppressive Agents; Male; Multiple Myeloma; Thalidomid

2014