thalidomide has been researched along with Genital Herpes in 4 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertrophic genital herpes is a disfiguring manifestation of a common infection seen in immunocompromised hosts that can be clinically mistaken for malignancy." | 2.44 | Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals. ( Bergin, C; Holmes, A; McMenamin, M; Mulcahy, F, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sbidian, E | 1 |
| Battistella, M | 1 |
| Legoff, J | 1 |
| Lafaurie, M | 1 |
| Bézier, M | 1 |
| Agbalika, F | 1 |
| Simon, F | 1 |
| Bouscarat, F | 1 |
| Cayuela, JM | 1 |
| Carcelain, G | 1 |
| Houhou, N | 1 |
| Bagot, M | 1 |
| Molina, JM | 1 |
| Janier, M | 1 |
| Bachelez, H | 1 |
| Charles, P | 1 |
| Richaud, C | 1 |
| Beley, S | 1 |
| Bodard, L | 1 |
| Simon, M | 1 |
| Holmes, A | 1 |
| McMenamin, M | 1 |
| Mulcahy, F | 1 |
| Bergin, C | 1 |
| Verberkmoes, A | 1 |
| Boer, K | 1 |
| Wertheim, PM | 1 |
| Bronkhorst, CM | 1 |
| Lange, JM | 1 |
1 review available for thalidomide and Genital Herpes
| Article | Year |
|---|---|
Thalidomide therapy for the treatment of hypertrophic herpes simplex virus-related genitalis in HIV-infected individuals.
Topics: Adult; Genitalia, Male; Herpes Genitalis; HIV Infections; Humans; Hypertrophy; Immunosuppressive Age | 2007 |
3 other studies available for thalidomide and Genital Herpes
| Article | Year |
|---|---|
Recalcitrant pseudotumoral anogenital herpes simplex virus type 2 in HIV-infected patients: evidence for predominant B-lymphoplasmocytic infiltration and immunomodulators as effective therapeutic strategy.
Topics: Acyclovir; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Herpes Genitalis; Herpesvi | 2013 |
Pseudotumoral recto-sigmoid herpes simplex virus type 2 in an HIV-infected patient: Dramatic improvement with thalidomide.
Topics: Adult; Female; Granuloma, Plasma Cell; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; Human | 2016 |
Thalidomide for genital ulcer in HIV-positive woman.
Topics: Adult; Female; Herpes Genitalis; HIV Seropositivity; HIV-1; Humans; Thalidomide; Ulcer; Vulvar Disea | 1996 |