thalidomide has been researched along with Gastroesophageal Reflux in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Few clinical trials have focused on treatments for IPF cough." | 2.55 | Etiology and treatment of cough in idiopathic pulmonary fibrosis. ( Horton, MR; Hughes, AH; Vigeland, CL, 2017) |
| "In thalidomide-treated SSc patients, plasma levels of IL-12 and TNF-alpha increased, while plasma IL-5 and IL-10 levels remained unchanged." | 1.31 | Immune stimulation in scleroderma patients treated with thalidomide. ( Kaplan, G; Moreira, A; Oliver, SJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vigeland, CL | 1 |
| Hughes, AH | 1 |
| Horton, MR | 1 |
| Ekfeldt, A | 1 |
| Carlsson, GE | 1 |
| Oliver, SJ | 1 |
| Moreira, A | 1 |
| Kaplan, G | 1 |
1 review available for thalidomide and Gastroesophageal Reflux
| Article | Year |
|---|---|
Etiology and treatment of cough in idiopathic pulmonary fibrosis.
Topics: Antitussive Agents; Comorbidity; Cough; Gastroesophageal Reflux; Humans; Idiopathic Pulmonary Fibros | 2017 |
2 other studies available for thalidomide and Gastroesophageal Reflux
| Article | Year |
|---|---|
Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study.
Topics: Abnormalities, Drug-Induced; Anodontia; Dental Care for Disabled; Dental Caries; DMF Index; Female; | 2008 |
Immune stimulation in scleroderma patients treated with thalidomide.
Topics: Adjuvants, Immunologic; Adult; Aged; Female; Gastroesophageal Reflux; Hematopoietic Cell Growth Fact | 2000 |