thalidomide has been researched along with Gastric Ulcer in 2 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide pretreatment significantly reduced the levels of pro-inflammatory cytokines [tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6], malondialdehyde (MDA) and myeloperoxidase (MPO) activity." | 1.42 | The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide. ( Amirshahrokhi, K; Khalili, AR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amirshahrokhi, K | 1 |
| Khalili, AR | 1 |
| BROWN, RA | 1 |
| WEST, GB | 1 |
2 other studies available for thalidomide and Gastric Ulcer
| Article | Year |
|---|---|
The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide.
Topics: Animals; Ethanol; Female; Histocytochemistry; Immunosuppressive Agents; Interleukin-1beta; Interleuk | 2015 |
EFFECT OF ACETYLSALICYLIC ACID ON FOETAL RATS.
Topics: Abnormalities, Drug-Induced; Aspirin; Caseins; Fetus; Pharmacology; Pregnancy; Rats; Research; Reser | 1964 |