thalidomide has been researched along with Gastric Diseases in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this report, we presented a Chinese patient with recurrent melena due to gastric angiodysplasia in HHT treated successfully with thalidomide." | 7.79 | Successful treatment of thalidomide for recurrent bleeding due to gastric angiodysplasia in hereditary hemorrhagic telangiectasia. ( Chen, Y; Du, Q; Wang, XY, 2013) |
| " In this report, we presented a Chinese patient with recurrent melena due to gastric angiodysplasia in HHT treated successfully with thalidomide." | 3.79 | Successful treatment of thalidomide for recurrent bleeding due to gastric angiodysplasia in hereditary hemorrhagic telangiectasia. ( Chen, Y; Du, Q; Wang, XY, 2013) |
| "Thalidomide pretreatment significantly reduced the levels of pro-inflammatory cytokines [tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6], malondialdehyde (MDA) and myeloperoxidase (MPO) activity." | 1.42 | The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide. ( Amirshahrokhi, K; Khalili, AR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, XY | 1 |
| Chen, Y | 1 |
| Du, Q | 1 |
| Draper, K | 1 |
| Kale, P | 1 |
| Martin, B | 1 |
| Kelly Cordero, R | 1 |
| Ha, R | 1 |
| Banerjee, D | 1 |
| Amirshahrokhi, K | 1 |
| Khalili, AR | 1 |
3 other studies available for thalidomide and Gastric Diseases
| Article | Year |
|---|---|
Successful treatment of thalidomide for recurrent bleeding due to gastric angiodysplasia in hereditary hemorrhagic telangiectasia.
Topics: Aged; Angiodysplasia; Gastrointestinal Hemorrhage; Humans; Male; Recurrence; Stomach Diseases; Telan | 2013 |
Thalidomide for treatment of gastrointestinal angiodysplasia in patients with left ventricular assist devices: case series and treatment protocol.
Topics: Adult; Aged; Angiodysplasia; Angiogenesis Inhibitors; Dose-Response Relationship, Drug; Female; Gast | 2015 |
The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide.
Topics: Animals; Ethanol; Female; Histocytochemistry; Immunosuppressive Agents; Interleukin-1beta; Interleuk | 2015 |