thalidomide has been researched along with Folic Acid Deficiency in 5 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedman, L | 1 |
| Shue, GM | 1 |
| Hove, EL | 1 |
| Dyban, AP | 1 |
| Akimova, IM | 1 |
| Onishi, T | 1 |
| Shtenberg, AI | 1 |
| Rajan, KT | 1 |
3 reviews available for thalidomide and Folic Acid Deficiency
| Article | Year |
|---|---|
[Experimental congenital heart diseases].
Topics: Animals; Chickens; Cricetinae; Dactinomycin; Disease Models, Animal; Dogs; Female; Folic Acid Defici | 1972 |
[Nutritional background and sensitivity of the organism to toxic substances].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Diet; Dietary Carbohydrates; Dietary | 1972 |
Human organ culture: applications in the screening of teratogenic drugs.
Topics: Abnormalities, Drug-Induced; Amino Acids; Anti-Bacterial Agents; Atmosphere; Carbon Dioxide; Culture | 1974 |
2 other studies available for thalidomide and Folic Acid Deficiency
| Article | Year |
|---|---|
RESPONSE OF RATS TO THALIDOMIDE AS AFFECTED BY RIBOFLAVIN OR FOLIC ACID DEFICIENCY.
Topics: Amino Acid Oxidoreductases; Avitaminosis; D-Amino-Acid Oxidase; Electron Transport Complex II; Flavi | 1965 |
[The significance of group B vitamins and genetic factors on the reaction of the rat embryo to thalidomide].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diet; Drug Hypersensitivity; E | 1966 |