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thalidomide and Folic Acid Deficiency

thalidomide has been researched along with Folic Acid Deficiency in 5 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friedman, L1
Shue, GM1
Hove, EL1
Dyban, AP1
Akimova, IM1
Onishi, T1
Shtenberg, AI1
Rajan, KT1

Reviews

3 reviews available for thalidomide and Folic Acid Deficiency

ArticleYear
[Experimental congenital heart diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:1

    Topics: Animals; Chickens; Cricetinae; Dactinomycin; Disease Models, Animal; Dogs; Female; Folic Acid Defici

1972
[Nutritional background and sensitivity of the organism to toxic substances].
    Gigiena i sanitariia, 1972, Volume: 37, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Diet; Dietary Carbohydrates; Dietary

1972
Human organ culture: applications in the screening of teratogenic drugs.
    Experimental embryology and teratology, 1974, Volume: 1, Issue:0

    Topics: Abnormalities, Drug-Induced; Amino Acids; Anti-Bacterial Agents; Atmosphere; Carbon Dioxide; Culture

1974

Other Studies

2 other studies available for thalidomide and Folic Acid Deficiency

ArticleYear
RESPONSE OF RATS TO THALIDOMIDE AS AFFECTED BY RIBOFLAVIN OR FOLIC ACID DEFICIENCY.
    The Journal of nutrition, 1965, Volume: 85, Issue:3

    Topics: Amino Acid Oxidoreductases; Avitaminosis; D-Amino-Acid Oxidase; Electron Transport Complex II; Flavi

1965
[The significance of group B vitamins and genetic factors on the reaction of the rat embryo to thalidomide].
    Arkhiv anatomii, gistologii i embriologii, 1966, Volume: 51, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diet; Drug Hypersensitivity; E

1966