Page last updated: 2024-11-05

thalidomide and Female Genital Neoplasms

thalidomide has been researched along with Female Genital Neoplasms in 4 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Research Excerpts

ExcerptRelevanceReference
"To define the efficacy of thalidomide on the overall survival of patients with metastatic recurrent gynecologic sarcomas."9.12Phase II trial of thalidomide for advanced and recurrent gynecologic sarcoma: a brief communication from the New York Phase II consortium. ( Blank, SV; Christos, P; Fields, AL; Goldberg, GL; Murgo, A; Runowicz, CD; Timmins, P; Wadler, S; Yi-Shin Kuo, D, 2006)
"To define the efficacy of thalidomide on the overall survival of patients with metastatic recurrent gynecologic sarcomas."5.12Phase II trial of thalidomide for advanced and recurrent gynecologic sarcoma: a brief communication from the New York Phase II consortium. ( Blank, SV; Christos, P; Fields, AL; Goldberg, GL; Murgo, A; Runowicz, CD; Timmins, P; Wadler, S; Yi-Shin Kuo, D, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WALKER, J1
Yi-Shin Kuo, D1
Timmins, P1
Blank, SV1
Fields, AL1
Goldberg, GL1
Murgo, A1
Christos, P1
Wadler, S1
Runowicz, CD1
Chon, HS1
Hu, W1
Kavanagh, JJ1
Ma, WW1
Jimeno, A1

Reviews

3 reviews available for thalidomide and Female Genital Neoplasms

ArticleYear
ADVANCES IN OBSTETRICS AND GYNAECOLOGY.
    The Practitioner, 1963, Volume: 191

    Topics: Anemia; Endocrinology; Erythroblastosis, Fetal; Female; Genital Neoplasms, Female; Gynecology; Hormo

1963
Targeted therapies in gynecologic cancers.
    Current cancer drug targets, 2006, Volume: 6, Issue:4

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineo

2006
Strategies for suppressing angiogenesis in gynecological cancers.
    Drugs of today (Barcelona, Spain : 1998), 2007, Volume: 43, Issue:4

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Dru

2007

Trials

1 trial available for thalidomide and Female Genital Neoplasms

ArticleYear
Phase II trial of thalidomide for advanced and recurrent gynecologic sarcoma: a brief communication from the New York Phase II consortium.
    Gynecologic oncology, 2006, Volume: 100, Issue:1

    Topics: Administration, Oral; Carcinosarcoma; Female; Genital Neoplasms, Female; Humans; Neoplasm Recurrence

2006