thalidomide has been researched along with Fatty Liver in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Fatty Liver: Lipid infiltration of the hepatic parenchymal cells resulting in a yellow-colored liver. The abnormal lipid accumulation is usually in the form of TRIGLYCERIDES, either as a single large droplet or multiple small droplets. Fatty liver is caused by an imbalance in the metabolism of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide-treated animals received thalidomide i." | 1.36 | The immunosuppressant drug, thalidomide, improves hepatic alterations induced by a high-fat diet in mice. ( Bartchewsky, W; Carvalho, Pde O; Cintra, DE; Compri, CM; Fornari, JV; Gambero, A; Pedrazzoli, J; Pinto, Lde F; Ribeiro, ML; Saad, MJ; Trevisan, M; Velloso, LA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pinto, Lde F | 1 |
| Compri, CM | 1 |
| Fornari, JV | 1 |
| Bartchewsky, W | 1 |
| Cintra, DE | 1 |
| Trevisan, M | 1 |
| Carvalho, Pde O | 1 |
| Ribeiro, ML | 1 |
| Velloso, LA | 1 |
| Saad, MJ | 1 |
| Pedrazzoli, J | 1 |
| Gambero, A | 1 |
1 other study available for thalidomide and Fatty Liver
| Article | Year |
|---|---|
The immunosuppressant drug, thalidomide, improves hepatic alterations induced by a high-fat diet in mice.
Topics: Animals; Biopsy, Needle; Blood Glucose; Diet; Dietary Fats; Disease Models, Animal; Fatty Liver; Imm | 2010 |