thalidomide has been researched along with Familial Mediterranean Fever in 1 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Familial Mediterranean Fever: A group of HEREDITARY AUTOINFLAMMATION DISEASES, characterized by recurrent fever, abdominal pain, headache, rash, PLEURISY; and ARTHRITIS. ORCHITIS; benign MENINGITIS; and AMYLOIDOSIS may also occur. Homozygous or compound heterozygous mutations in marenostrin gene encoding PYRIN result in autosomal recessive transmission; simple heterozygous, autosomal dominant form of the disease also exists with mutations in the same gene.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The efficacy and adverse events were evaluated and recorded every 3 months." | 1.91 | Efficacy and safety of thalidomide in children with monogenic autoinflammatory diseases: a single-center, real-world-evidence study. ( Gao, S; Gou, L; Li, J; Ma, M; Song, H; Wang, C; Wang, L; Wang, W; Yu, Z; Zhang, C; Zhong, L; Zhou, Y, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, C | 1 |
| Yu, Z | 1 |
| Gao, S | 1 |
| Ma, M | 1 |
| Gou, L | 1 |
| Wang, C | 1 |
| Wang, L | 1 |
| Li, J | 1 |
| Zhong, L | 1 |
| Zhou, Y | 1 |
| Wang, W | 1 |
| Song, H | 1 |
1 other study available for thalidomide and Familial Mediterranean Fever
| Article | Year |
|---|---|
Efficacy and safety of thalidomide in children with monogenic autoinflammatory diseases: a single-center, real-world-evidence study.
Topics: Adenosine Deaminase; Child; Cryopyrin-Associated Periodic Syndromes; Familial Mediterranean Fever; H | 2023 |