thalidomide has been researched along with Facial Palsy in 17 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Earlier studies have shown that individuals with thalidomide embryopathy can have skeletal deformities, ear and eye aberrations, and facial palsy." | 7.78 | Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics. ( Kiliaridis, S; Sjögreen, L, 2012) |
| "Earlier studies have shown that individuals with thalidomide embryopathy can have skeletal deformities, ear and eye aberrations, and facial palsy." | 3.78 | Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics. ( Kiliaridis, S; Sjögreen, L, 2012) |
| "A previous study of 86 thalidomide-affected subjects with ophthalmic manifestations revealed the unexpected finding of autism in 4 of the 5 severely retarded individuals." | 3.70 | The puzzle of autism: an ophthalmologic contribution. ( Gillberg, C; Johansson, M; Miller, MT; Nilsson, EW; Strömland, K, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (88.24) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sjögreen, L | 1 |
| Kiliaridis, S | 1 |
| ROSSBERG, G | 1 |
| PARTSCH, CJ | 2 |
| D AVIGNON, M | 1 |
| BARR, B | 1 |
| JORGENSEN, MB | 1 |
| KRISTENSEN, HK | 1 |
| BUCH, NH | 1 |
| TERRAHE, K | 2 |
| MIEHLKE, A | 1 |
| Nessel, E | 1 |
| Suwelack, K | 1 |
| Miller, MT | 1 |
| Strömland, K | 1 |
| Gillberg, C | 1 |
| Johansson, M | 1 |
| Nilsson, EW | 1 |
| Takemori, S | 1 |
| Tanaka, Y | 1 |
| Suzuki, JI | 1 |
| Phelps, PD | 1 |
| Browne, SG | 1 |
| Elsahy, NI | 1 |
| Mongeau, M | 1 |
| Gingras, G | 1 |
| Sherman, ED | 1 |
| Hebert, B | 1 |
| Hutchison, J | 1 |
| Corriveau, C | 1 |
| Horstmann, W | 1 |
2 reviews available for thalidomide and Facial Palsy
| Article | Year |
|---|---|
[EAR DEFORMITIES AND CONTERGAN (WITH A CONTRIBUTION ON THE DEVELOPMENT OF THE EAR AND FACIAL NERVE)].
Topics: Ear Deformities, Acquired; Ear, External; Ectromelia; Facial Nerve; Facial Paralysis; Thalidomide | 1963 |
Summary of recent abstracts. 8. Leprosy.
Topics: Animals; Facial Paralysis; Genetics, Microbial; Hepatitis B Antigens; Humans; Leprosy; Mice; Mycobac | 1972 |
15 other studies available for thalidomide and Facial Palsy
| Article | Year |
|---|---|
Facial palsy in individuals with thalidomide embryopathy: frequency and characteristics.
Topics: Abnormalities, Drug-Induced; Adult; Case-Control Studies; Facial Expression; Facial Paralysis; Femal | 2012 |
[EAR DEFORMITIES IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Congenital Abnormalities; Cryptorchidism; Ear Deformities | 1964 |
EAR ABNORMALITIES AND CRANIAL NERVE PALSIES IN THALIDOMIDE CHILDREN.
Topics: Abnormalities, Drug-Induced; Child; Cranial Nerve Diseases; Cranial Nerves; Deafness; Ear Deformitie | 1964 |
THALIDOMIDE-INDUCED APLASIA OF THE INNER EAR.
Topics: Abnormalities, Drug-Induced; Ear Deformities, Acquired; Ear, External; Ear, Inner; Facial Paralysis; | 1964 |
[ABNORMALITIES OF THE INTERNAL AND MIDDLE EAR AS A SEQUEL TO THALIDOMIDE EMBRYOPATHY--RESULTS OF TOMOGRAPHIC EXAMINATIONS OF THE EAR].
Topics: Abnormalities, Drug-Induced; Cochlear Nerve; Ear, Middle; Facial Nerve; Facial Paralysis; Fetal Dise | 1965 |
ANATOMY AND CLINICAL ASPECTS OF THE FACIAL NERVE.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Anatomy; Ear; Facial Nerve; Facial Paralysis; Humans; O | 1965 |
[Otoneurological studies of facial nerve paralysis in thalidomide dysplasia].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Child; Child, Preschool; Ear Deformities, Acquired; Ele | 1967 |
The puzzle of autism: an ophthalmologic contribution.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Autistic Disorder; Child; Eye Diseases; Facial Paral | 1998 |
Thalidomide anomalies of the ear.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Adolescent; Child; Deafness; Ear; Ear, External; Ear, I | 1976 |
Congenital lesions of the inner ear, demonstrated by tomography.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Child; Cochlea; Ear; Ear, I | 1974 |
Moebius syndrome associated with the mother taking thalidomide during gestation. Case report.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Anxiety; Facial Expression; Fa | 1973 |
[Diagnosis of malformations of the ear and temporal bone].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos | 1972 |
[Congenital ear abnormalities as a cause of deafness].
Topics: Abnormalities, Drug-Induced; Animals; Anura; Cats; Chick Embryo; Congenital Abnormalities; Cricetina | 1969 |
Medical and psychosocial aspects of the habilitation of thalidomide children.
Topics: Abnormalities, Drug-Induced; Adult; Artificial Limbs; Child, Preschool; Deafness; Ear Deformities, A | 1966 |
[Reference to central nervous system damage within the context of thalidomide embryopathy. Pathological-anatomic, electroencephalographic and neurologic findings].
Topics: Abnormalities, Drug-Induced; Central Nervous System Diseases; Child, Preschool; Ear Deformities, Acq | 1966 |