Page last updated: 2024-11-05

thalidomide and Facial Asymmetry

thalidomide has been researched along with Facial Asymmetry in 2 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Facial Asymmetry: Congenital or acquired asymmetry of the face.

Research Excerpts

ExcerptRelevanceReference
"Cranial nerve palsy/paresis was only seen in HFM and thalidomide-induced malformations."1.30Teratological studies on craniofacial malformations. ( Jacobsson, C, 1997)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobsson, C2
Granström, G1

Other Studies

2 other studies available for thalidomide and Facial Asymmetry

ArticleYear
Teratological studies on craniofacial malformations.
    Swedish dental journal. Supplement, 1997, Volume: 121

    Topics: Alkaline Phosphatase; Aminopropionitrile; Amniotic Fluid; Animals; Branchial Region; Cartilage; Clef

1997
Clinical appearance of spontaneous and induced first and second branchial arch syndromes.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 1997, Volume: 31, Issue:2

    Topics: Adult; Animals; Branchial Region; Craniofacial Dysostosis; Disease Models, Animal; Facial Asymmetry;

1997