thalidomide has been researched along with External Ophthalmoplegia in 13 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One third of Swedes with thalidomide embryopathy have sixth and seventh cranial nerve palsy, named Möbius syndrome/sequence, and some of them suffer from autism." | 4.80 | [Eye muscle paralysis can increase the knowledge on autism]. ( Strömland, K, 2000) |
| "Although peripheral neuropathies in children are often of genetic origin, acquired causes should be carefully looked for and ruled out also in the pediatric age." | 2.58 | Peripheral neuropathy and gastroenterologic disorders: an overview on an underrecognized association. ( De' Angelis, GL; Di Mario, F; Fusco, C; Gaiani, F; Leandro, G; Pisani, F; Spagnoli, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spagnoli, C | 1 |
| Pisani, F | 1 |
| Di Mario, F | 1 |
| Leandro, G | 1 |
| Gaiani, F | 1 |
| De' Angelis, GL | 1 |
| Fusco, C | 1 |
| CULLEN, JF | 1 |
| PAPST, W | 1 |
| SCHMIDT, JG | 1 |
| MIEHLKE, A | 1 |
| Strömland, K | 1 |
| Murphy, R | 1 |
| Mohr, P | 1 |
| Phelps, PD | 1 |
| Zetterström, B | 1 |
| Rafuse, EV | 1 |
| Arstikaitis, M | 1 |
| Brent, HP | 1 |
| Terrahe, K | 1 |
| Uemura, Y | 1 |
| Tamura, H | 1 |
| Okada, Y | 1 |
| Horstmann, W | 1 |
2 reviews available for thalidomide and External Ophthalmoplegia
| Article | Year |
|---|---|
Peripheral neuropathy and gastroenterologic disorders: an overview on an underrecognized association.
Topics: Antibodies, Monoclonal; Antirheumatic Agents; Campylobacter Infections; Celiac Disease; Child; Comor | 2018 |
[Eye muscle paralysis can increase the knowledge on autism].
Topics: Abnormalities, Multiple; Adult; Animals; Autistic Disorder; Facial Nerve; Female; Humans; Hypnotics | 2000 |
11 other studies available for thalidomide and External Ophthalmoplegia
| Article | Year |
|---|---|
OCULAR DEFECTS IN THALIDOMIDE BABIES.
Topics: Abnormalities, Drug-Induced; Eye; Eye Diseases; Female; Humans; Infant; Infant, Newborn; Infant, New | 1964 |
[THALIDOMIDE AND CONGENITAL ABNORMALITIES OF THE EYE].
Topics: Abnormalities, Drug-Induced; Anophthalmos; Child; Eye Diseases; Infant; Learning; Microphthalmos; Op | 1964 |
[OCULOMOTOR PARALYSIS IN THALIDOMIDE EMBRYOPATHY].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Child; Female; Fetal Diseases; Ophthalmoplegia | 1964 |
ANATOMY AND CLINICAL ASPECTS OF THE FACIAL NERVE.
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Anatomy; Ear; Facial Nerve; Facial Paralysis; Humans; O | 1965 |
Two congenital neurological abnormalities caused by thalidomide.
Topics: Abnormalities, Drug-Induced; Adolescent; Brain Diseases; Female; Humans; Ophthalmoplegia; Thalidomid | 1977 |
Congenital lesions of the inner ear, demonstrated by tomography.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Adult; Child; Cochlea; Ear; Ear, I | 1974 |
Ocular malformations caused by thalidomide.
Topics: Child; Child, Preschool; Eye Abnormalities; Eye Diseases; Female; Humans; Male; Microphthalmos; Nyst | 1966 |
Ocular findings in thalidomide children.
Topics: Abnormalities, Drug-Induced; Blepharoptosis; Canada; Coloboma; Eye Abnormalities; Female; Humans; In | 1967 |
[Diagnosis of malformations of the ear and temporal bone].
Topics: Abducens Nerve; Abnormalities, Drug-Induced; Abnormalities, Multiple; Audiometry; Craniofacial Dysos | 1972 |
[Congenital gustolacrimal syndrome complicated with bilateral Duane's syndrome and gustolacrimal reflex, with special emphasis on the etiology].
Topics: Child; Child, Preschool; Female; Humans; Male; Ophthalmoplegia; Pregnancy; Reflex, Abnormal; Taste; | 1969 |
[Reference to central nervous system damage within the context of thalidomide embryopathy. Pathological-anatomic, electroencephalographic and neurologic findings].
Topics: Abnormalities, Drug-Induced; Central Nervous System Diseases; Child, Preschool; Ear Deformities, Acq | 1966 |