thalidomide has been researched along with Experimental Mammary Neoplasms in 7 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide has proven to exert anti-inflammatory, anti-proliferative and anti-angiogenic activities in both neoplastic and non-neoplastic conditions." | 5.38 | Thalidomide attenuates mammary cancer associated-inflammation, angiogenesis and tumor growth in mice. ( Alves Neves Diniz Ferreira, M; Cândida Araújo E Silva, A; da Silva Vieira, T; Dantas Cassali, G; Fonseca de Carvalho, L; Maria de Souza, C; Passos Andrade, S; Teresa Paz Lopes, M, 2012) |
| "Thalidomide (Thal) can suppress the growth of established, as well as explanted tumors in mice." | 1.38 | Thalidomide delayed the ability of 4T1 cells to amass into tumors in Balb/c mice. ( Baghian, A; Israyelyan, A; Kearney, MT; Sandoval, F; Shannon, EJ, 2012) |
| "Thalidomide has proven to exert anti-inflammatory, anti-proliferative and anti-angiogenic activities in both neoplastic and non-neoplastic conditions." | 1.38 | Thalidomide attenuates mammary cancer associated-inflammation, angiogenesis and tumor growth in mice. ( Alves Neves Diniz Ferreira, M; Cândida Araújo E Silva, A; da Silva Vieira, T; Dantas Cassali, G; Fonseca de Carvalho, L; Maria de Souza, C; Passos Andrade, S; Teresa Paz Lopes, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ionov, ID | 1 |
| Gorev, NP | 1 |
| Roslavtseva, LA | 1 |
| Frenkel, DD | 1 |
| de Souza, CM | 1 |
| Araújo e Silva, AC | 1 |
| de Jesus Ferraciolli, C | 1 |
| Moreira, GV | 1 |
| Campos, LC | 1 |
| dos Reis, DC | 1 |
| Lopes, MT | 1 |
| Ferreira, MA | 1 |
| Andrade, SP | 1 |
| Cassali, GD | 1 |
| Israyelyan, A | 2 |
| Shannon, EJ | 2 |
| Baghian, A | 2 |
| Kearney, MT | 2 |
| Kousoulas, KG | 1 |
| Sandoval, F | 1 |
| Maria de Souza, C | 1 |
| Fonseca de Carvalho, L | 1 |
| da Silva Vieira, T | 1 |
| Cândida Araújo E Silva, A | 1 |
| Teresa Paz Lopes, M | 1 |
| Alves Neves Diniz Ferreira, M | 1 |
| Passos Andrade, S | 1 |
| Dantas Cassali, G | 1 |
| Mückter, H | 2 |
| Moré, E | 2 |
| Frankus, E | 1 |
| Kollmer, WE | 1 |
| Staemmler, M | 1 |
7 other studies available for thalidomide and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Cetirizine and thalidomide synergistically inhibit mammary tumorigenesis and angiogenesis in 7,12-dimethylbenz(a)anthracene-treated rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Apoptosis; Blotting, Western; Ce | 2018 |
Combination therapy with carboplatin and thalidomide suppresses tumor growth and metastasis in 4T1 murine breast cancer model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carboplatin; Cell Line, Tumor; D | 2014 |
Thalidomide suppressed the growth of 4T1 cells into solid tumors in Balb/c mice in a combination therapy with the oncolytic fusogenic HSV-1 OncdSyn.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Combined Modality Therapy; Fema | 2009 |
Thalidomide delayed the ability of 4T1 cells to amass into tumors in Balb/c mice.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Female; Mammary Neoplasms, Experimental; Mice; M | 2012 |
Thalidomide attenuates mammary cancer associated-inflammation, angiogenesis and tumor growth in mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Female; Fibroblast Growth Factor 1; Gene Exp | 2012 |
[Thalidomide and cancer].
Topics: Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chlormadinone Acetate; Chlorpromazine; Cyclophos | 1966 |
[Experimental studies with cyclic imides in dimethylbenzanthracene tumors of Sprague-Dawley rats].
Topics: Animals; Benz(a)Anthracenes; Body Weight; Female; Hypophysectomy; Imides; Mammary Neoplasms, Experim | 1967 |