thalidomide has been researched along with Esophageal and Gastric Varices in 3 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Esophageal and Gastric Varices: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silver, R | 1 |
| Karajeh, MA | 1 |
| Hurlstone, DP | 1 |
| Stephenson, TJ | 1 |
| Ray-Chaudhuri, D | 1 |
| Gleeson, DC | 1 |
| Bodokh, I | 1 |
| Lacour, JP | 1 |
| Rainero, C | 1 |
| Castanet, J | 1 |
| Michiels, JF | 1 |
| Ortonne, JP | 1 |
3 other studies available for thalidomide and Esophageal and Gastric Varices
| Article | Year |
|---|---|
Current treatment of myelofibrosis.
Topics: Blood Transfusion; Bone Marrow Transplantation; Clinical Trials as Topic; Dexamethasone; Disease Man | 2005 |
Refractory bleeding from portal hypertensive gastropathy: a further novel role for thalidomide therapy?
Topics: Angiogenesis Inhibitors; Biopsy; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans | 2006 |
[Efficacy of thalidomide against esophageal ulceration in HIV infection].
Topics: Adult; Esophageal and Gastric Varices; HIV Infections; Humans; Male; Stomatitis, Aphthous; Thalidomi | 1993 |