thalidomide has been researched along with Esophageal Diseases in 21 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Esophageal Diseases: Pathological processes in the ESOPHAGUS.
Excerpt | Relevance | Reference |
---|---|---|
"A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating esophageal aphthous ulceration in persons infected with human immunodeficiency virus (HIV)." | 9.09 | Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. ( Basgoz, N; Chernoff, M; Fahey, JL; Fox, L; Hooton, TM; Jackson, JB; Jacobson, JM; MacPhail, LA; Sha, BE; Shikuma, CM; Simpson, DM; Spritzler, J; Trapnell, CB; Wohl, DA; Wu, AW, 1999) |
"Thalidomide appears to be highly effective for oropharyngeal apthous ulcers in HIV-infected patients." | 9.08 | A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers. ( Alexander, LN; Wilcox, CM, 1997) |
"A multicenter, double-blind, randomized, placebo-controlled clinical trial was conducted to determine the safety and efficacy of thalidomide for treating esophageal aphthous ulceration in persons infected with human immunodeficiency virus (HIV)." | 5.09 | Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group. ( Basgoz, N; Chernoff, M; Fahey, JL; Fox, L; Hooton, TM; Jackson, JB; Jacobson, JM; MacPhail, LA; Sha, BE; Shikuma, CM; Simpson, DM; Spritzler, J; Trapnell, CB; Wohl, DA; Wu, AW, 1999) |
"Thalidomide appears to be highly effective for oropharyngeal apthous ulcers in HIV-infected patients." | 5.08 | A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers. ( Alexander, LN; Wilcox, CM, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 16 (76.19) | 18.2507 |
2000's | 4 (19.05) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (4.76) | 2.80 |
Authors | Studies |
---|---|
Chen, R | 1 |
Liu, X | 1 |
Hao, J | 1 |
Dadban, A | 1 |
Guillot, B | 1 |
Atiq, M | 1 |
Neff, GW | 1 |
Argyropoulos, C | 1 |
Schroer, M | 1 |
Kemmer, N | 1 |
Weber, F | 1 |
Buell, J | 1 |
Thompson, C | 1 |
Sire, S | 1 |
Fraisse, P | 1 |
Rey, D | 1 |
Jacquemin, C | 1 |
Kempf, G | 1 |
Partisani, M | 1 |
Lang, JM | 1 |
Naum, SM | 1 |
Molloy, PJ | 1 |
Kania, RJ | 1 |
McGarr, J | 1 |
Van Thiel, DH | 1 |
Couderc, LJ | 1 |
Balloul, E | 1 |
Caubarrere, I | 1 |
Domingo, P | 1 |
Ris, J | 1 |
López-Contreras, J | 1 |
DeVincenzo, JP | 1 |
Burchet, SK | 1 |
Louvel, D | 1 |
Musso, S | 1 |
Métivier, S | 1 |
Croizet, O | 1 |
Rouquet, RM | 1 |
Massip, P | 1 |
Escourrou, J | 1 |
Frexinos, J | 1 |
Bellomo, A | 1 |
Schorr-Lesnick, B | 1 |
Alexander, LN | 1 |
Wilcox, CM | 1 |
Jibaly, RM | 1 |
Moallem, H | 1 |
Fikrig, SM | 1 |
Rabinowitz, SS | 1 |
Jacobson, JM | 1 |
Spritzler, J | 1 |
Fox, L | 1 |
Fahey, JL | 1 |
Jackson, JB | 1 |
Chernoff, M | 1 |
Wohl, DA | 1 |
Wu, AW | 1 |
Hooton, TM | 1 |
Sha, BE | 1 |
Shikuma, CM | 1 |
MacPhail, LA | 1 |
Simpson, DM | 1 |
Trapnell, CB | 1 |
Basgoz, N | 1 |
Ollivier, S | 1 |
Bonnet, J | 1 |
Lemann, M | 1 |
Coffin, JC | 1 |
Modigliani, R | 1 |
Jian, R | 1 |
Bertheau, P | 1 |
Flejou, JF | 1 |
Ryan, J | 2 |
Ginsburg, PM | 1 |
Hanan, I | 1 |
Ehrenpreis, ED | 1 |
Colman, J | 1 |
Pedersen, J | 1 |
Georghiou, PR | 1 |
Kemp, RJ | 1 |
Bernardo, P | 1 |
Arrizabalaga, J | 1 |
Iribarren, JA | 1 |
Garde, C | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection[NCT00000790] | Phase 2 | 164 participants | Interventional | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 trials available for thalidomide and Esophageal Diseases
Article | Year |
---|---|
Thalidomide effective for AIDS-related oral ulcers.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Esophageal Diseases; Humans; Placebos; Sto | 1995 |
A prospective trial of thalidomide for the treatment of HIV-associated idiopathic esophageal ulcers.
Topics: Adult; Anti-Ulcer Agents; Esophageal Diseases; Follow-Up Studies; HIV Infections; Humans; Prospectiv | 1997 |
Thalidomide for the treatment of esophageal aphthous ulcers in patients with human immunodeficiency virus infection. National Institute of Allergy and Infectious Disease AIDS Clinical Trials Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antigens, CD; Double-Blind Method; Esophageal Diseases; E | 1999 |
Thalidomide effective in treating AIDS-related mouth ulcers.
Topics: Adult; AIDS-Related Opportunistic Infections; Esophageal Diseases; Female; Humans; Immunosuppressive | 1996 |
17 other studies available for thalidomide and Esophageal Diseases
Article | Year |
---|---|
Esophageal Sinus in a Patient With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
Topics: Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Cyclophosphamide; Deglutition Diso | 2020 |
Oesophageal involvement in familial benign chronic pemphigus.
Topics: Administration, Oral; Diagnosis, Differential; Esophageal Diseases; Esophagoscopy; Female; Humans; M | 2006 |
Successful treatment with thalidomide in a liver transplant recipient with giant esophageal ulcers.
Topics: Aged; Esophageal Diseases; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Thalidomid | 2006 |
[Efficacy of thalidomide in the treatment of esophageal ulcers in human immunodeficiency virus infection].
Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Fatal Outcome; HIV Infections; HIV S | 1995 |
Use of thalidomide in treatment and maintenance of idiopathic esophageal ulcers in HIV+ individuals.
Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Female; HIV Seropositivity; HIV-1; H | 1995 |
Esophageal ulcers in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Anti-Ulcer Agents; Esophageal Diseases; Humans; Thalidomide; Ulc | 1996 |
Esophageal ulcers in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Anti-Ulcer Agents; Esophageal Diseases; Humans; Thalidomide; Ulc | 1996 |
Prolonged thalidomide therapy for human immunodeficiency virus-associated recurrent severe esophageal and oral aphthous ulcers.
Topics: AIDS-Related Opportunistic Infections; CD4 Lymphocyte Count; Child, Preschool; Esophageal Diseases; | 1996 |
Idiopathic esophageal ulceration associated with human immunodeficiency virus infection: efficacy of thalidomide treatment.
Topics: Adult; Anti-Ulcer Agents; Esophageal Diseases; HIV Infections; Humans; Male; Thalidomide; Ulcer | 1996 |
Thalidomide treatment for idiopathic esophageal ulcers in patients with HIV.
Topics: Acquired Immunodeficiency Syndrome; Adult; Endoscopy, Digestive System; Esophageal Diseases; Humans; | 1996 |
Steroid-resistant idiopathic esophageal ulcer in a child with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Candidiasis; Child, Preschool; Drug Resistance; Esophageal Disea | 1998 |
Idiopathic giant oesophageal ulcer in an immunocompetent patient. The efficacy of thalidomide treatment.
Topics: Esophageal Diseases; Humans; Immunocompetence; Immunosuppressive Agents; Male; Middle Aged; Thalidom | 1999 |
Thalidomide treatment of oesophageal ulceration.
Topics: Esophageal Diseases; Humans; Immunosuppressive Agents; Thalidomide; Ulcer | 2000 |
Treatment of severe esophageal Crohn's disease with thalidomide.
Topics: Aged; Aged, 80 and over; Crohn Disease; Esophageal Diseases; Female; Humans; Severity of Illness Ind | 2001 |
Thalidomide to treat esophageal ulcer in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Humans; Male; Thalidomide; Ulcer | 1992 |
HIV-associated oesophageal ulcers treated with thalidomide.
Topics: Esophageal Diseases; HIV Infections; Humans; Male; Middle Aged; Thalidomide; Ulcer | 1990 |
[Effectiveness of thalidomide in non specific esophageal ulcer in patients with acquired immunodeficiency syndrome].
Topics: Acquired Immunodeficiency Syndrome; Adult; Esophageal Diseases; Humans; Male; Thalidomide; Ulcer | 1990 |