Page last updated: 2024-11-05

thalidomide and Erythema

thalidomide has been researched along with Erythema in 10 studies

Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.

Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.

Research Excerpts

ExcerptRelevanceReference
"A Burmese boy being treated with dapsone (diaminodiphenylsulfone [DDS]), 100 mg daily, for lepromatous leprosy had a fatal reaction to the drug 3 weeks after therapy was started."7.66Fatal reaction to dapsone during treatment of leprosy. ( Borkowsky, W; Bullock, WE; Frey, HM; Gershon, AA, 1981)
"A man in his late 60s who had received the first cycle of a chemotherapeutic regimen of ixazomib, lenalidomide, and dexamethasone for multiple myeloma presented to the dermatologic clinic with a 10-day history of fever and tender lesions on the neck and trunk."4.31Fever, Pancytopenia, and Tender Erythematous Plaques in a Patient With Multiple Myeloma. ( Katayama, S; Ota, M; Yamaga, M, 2023)
"These data suggest that the anti-inflammatory effects of thalidomide can affect UVB injury, and may, in part, explain its action in photosensitivity diseases such as cutaneous lupus erythematosus."3.72Thalidomide inhibits UVB-induced mouse keratinocyte apoptosis by both TNF-alpha-dependent and TNF-alpha-independent pathways. ( Brenneman, S; Burns, R; Gaines, E; Gaspari, A; Haake, A; Lu, KQ; Vink, A, 2003)
"A Burmese boy being treated with dapsone (diaminodiphenylsulfone [DDS]), 100 mg daily, for lepromatous leprosy had a fatal reaction to the drug 3 weeks after therapy was started."3.66Fatal reaction to dapsone during treatment of leprosy. ( Borkowsky, W; Bullock, WE; Frey, HM; Gershon, AA, 1981)
"Thalidomide was first introduced in the 1950s as a sedative but was quickly removed from the market after it was linked to cases of severe birth defects."2.43Thalidomide: dermatological indications, mechanisms of action and side-effects. ( Hsu, S; Huang, DB; Pang, KR; Tyring, SK; Wu, JJ, 2005)
"Off-label use of lenalidomide (Len) in chronic lymphocytic leukemia (CLL) is becoming increasingly frequent."1.37Dermatological complications following initiation of lenalidomide in a patient with chronic lymphocytic leukaemia. ( Giorgadze, T; Tageja, N; Zonder, J, 2011)
"Oral mucositis is a frequent side-effect of cancer therapy."1.33Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters. ( Augusto, RF; Brito, GA; Cunha, FQ; Falcão, BA; Leitão, BT; Lima, V; Rebouças, CG; Ribeiro, RA; Souza, ML, 2005)
" Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes."1.32Reactions and their management. ( Ganapati, R; Pai, VV, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Yamaga, M1
Katayama, S1
Ota, M1
Jia, E1
Wei, J1
Geng, H1
Qiu, X1
Xie, J1
Xiao, Y1
Zhong, L1
Xiao, M1
Zhang, Y1
Jiang, Y1
Zhang, J1
Fabbro, SK1
Kaffenberger, BH1
Tageja, N1
Giorgadze, T1
Zonder, J1
Lu, KQ1
Brenneman, S1
Burns, R1
Vink, A1
Gaines, E1
Haake, A1
Gaspari, A1
Ganapati, R1
Pai, VV1
Lima, V1
Brito, GA1
Cunha, FQ1
Rebouças, CG1
Falcão, BA1
Augusto, RF1
Souza, ML1
Leitão, BT1
Ribeiro, RA1
Wu, JJ1
Huang, DB1
Pang, KR1
Hsu, S1
Tyring, SK1
Chiou, CC1
Shih, IH1
Chang, YC1
Lee, JC1
Kuo, SC1
Hong, HS1
Yang, CH1
Frey, HM1
Gershon, AA1
Borkowsky, W1
Bullock, WE1

Reviews

2 reviews available for thalidomide and Erythema

ArticleYear
Diffuse pruritic erythema as a clinical manifestation in anti-SAE antibody-associated dermatomyositis: a case report and literature review.
    Clinical rheumatology, 2019, Volume: 38, Issue:8

    Topics: Antibodies; Asian People; Cyclosporine; Dermatomyositis; Erythema; Female; Humans; Methotrexate; Mid

2019
Thalidomide: dermatological indications, mechanisms of action and side-effects.
    The British journal of dermatology, 2005, Volume: 153, Issue:2

    Topics: Adult; Behcet Syndrome; Dermatologic Agents; Erythema; Graft vs Host Disease; Histiocytosis, Langerh

2005

Other Studies

8 other studies available for thalidomide and Erythema

ArticleYear
Fever, Pancytopenia, and Tender Erythematous Plaques in a Patient With Multiple Myeloma.
    JAMA dermatology, 2023, 07-01, Volume: 159, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Erythema; Humans; Lenalidomide; Multi

2023
Resident rounds part III: plasma cell leukemia with initial cutaneous presentation.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Bortezomib; Dexamethasone;

2014
Dermatological complications following initiation of lenalidomide in a patient with chronic lymphocytic leukaemia.
    Internal medicine journal, 2011, Volume: 41, Issue:3

    Topics: Erythema; Female; Humans; Lenalidomide; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Sweet S

2011
Thalidomide inhibits UVB-induced mouse keratinocyte apoptosis by both TNF-alpha-dependent and TNF-alpha-independent pathways.
    Photodermatology, photoimmunology & photomedicine, 2003, Volume: 19, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Disease Models, Animal; Dose-Response R

2003
Reactions and their management.
    Journal of the Indian Medical Association, 2004, Volume: 102, Issue:12

    Topics: Arthritis; Cicatrix; Clofazimine; Dose-Response Relationship, Drug; Drug-Related Side Effects and Ad

2004
Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters.
    European journal of oral sciences, 2005, Volume: 113, Issue:3

    Topics: Abscess; Animals; Antimetabolites, Antineoplastic; Cricetinae; Disease Models, Animal; Edema; Erythe

2005
Thalidomide-induced severe facial erythema in a patient with hepatocellular carcinoma.
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Aged; Carcinoma, Hepatocellular; Erythema; Humans; Immunosuppressive Agents; Liver Neoplasms; Male;

2007
Fatal reaction to dapsone during treatment of leprosy.
    Annals of internal medicine, 1981, Volume: 94, Issue:6

    Topics: Adolescent; Dapsone; Erythema; Humans; Leprosy; Male; Skin; Thalidomide

1981